Innovative drug development for headache disorders / edited by Jes Olesen, Nabih Ramadan.

Contributor(s):

Material type: Text

TextSeries: Frontiers in headache research ; v. 16.Publication details: Oxford ; New York : Oxford University Press, 2008.Description: 1 online resource (xii, 227 pages) : illustrationsContent type:

text

Media type:

computer

Carrier type:

online resource

ISBN:

9780191564628
0191564621

Subject(s): Genre/Form:

Electronic books.

Additional physical formats: Print version:: Innovative drug development for headache disorders.DDC classification:

616.8/491061 22

LOC classification:

RC392 .I558 2008eb

NLM classification:

W1
WL 342

Online resources:

Click here to access online

Contents:

Effectiveness of different steroid dosage in Tolosa-Hunt syndrome with different phenotypes: some critical points about the new International Headache Society classification / E. Marchioni [and others] -- Discussion summary: trial methodology / Jes Olesen -- Inducible nitric oxide synthase and development of new migraine treatments / Boris A. Chizh -- Mechanisms of cortical spreading depression as targets for migraine therapy / Kevin C. Brennan and Andrew C. Charles -- Tonabersat / Peter R. Blower and Paul C. Sharpe -- Discussion summary: nitric oxide and spreading depression modulators / Nabih Ramadan -- Calcitonin gene-related peptide: relevance for migraine / Jes Olesen and Inger Jansen-Olesen.

KATP channels and migraine / Inger Jansen-Olesen and Kenneth Beri Ploug -- Antiepileptic drugs and migraine / Michael A. Rogawski -- Discussion summary : ion channel modulators and antiepileptics / Pramod R. Saxena -- Innovative drug development for headache disorders : glutamate / Kirk W. Johnson [and others] -- The modulation of TRPV1 channels by cannabinoid1 receptors / Beatriz Fioravanti and Todd W. Vanderah -- Future targets for headache therapy: prostanoids / Christian Waeber -- Role of anandamide in the modulation of nitroglycerin-induced hyperalgesia: a study in the rat / Cristina Tassorelli [and others].

Summary: Migraine treatment improved considerably with the advent of the 'triptans' in the 1990s. While the drugs used previously for headache treatment had efficacy, some compounds had bothersome side effects and their overuse could lead to severe complications. In the early days of the triptans, it was widely presumed that migraine was no longer a treatment problem. However, it has gradually been recognized that a significant proportion of patients are not responsive to triptans or do not tolerate them.

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Item type	Home library	Collection	Call number	Materials specified	Status	Date due	Barcode
Electronic-Books	OPJGU Sonepat- Campus	E-Books EBSCO			Available

Includes bibliographical references and index.

Print version record.

Migraine treatment improved considerably with the advent of the 'triptans' in the 1990s. While the drugs used previously for headache treatment had efficacy, some compounds had bothersome side effects and their overuse could lead to severe complications. In the early days of the triptans, it was widely presumed that migraine was no longer a treatment problem. However, it has gradually been recognized that a significant proportion of patients are not responsive to triptans or do not tolerate them.

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