MARC details
| 000 -LEADER |
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| fixed length control field |
04782naaaa2200385uu 4500 |
| 001 - CONTROL NUMBER |
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| control field |
https://directory.doabooks.org/handle/20.500.12854/54505 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20220714194156.0 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
978-2-88945-378-8 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9782889453788 |
| 024 7# - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.3389/978-2-88945-378-8 |
| Terms of availability |
doi |
| 041 0# - LANGUAGE CODE |
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| Language code of text/sound track or separate title |
English |
| 042 ## - AUTHENTICATION CODE |
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| Authentication code |
dc |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
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| Personal name |
Atsuyoshi Shimada |
| Relator code |
auth |
| 9 (RLIN) |
1621192 |
| 245 10 - TITLE STATEMENT |
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| Title |
Neuroimmune Interface in Health and Diseases |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
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| Name of publisher, distributor, etc |
Frontiers Media SA |
| Date of publication, distribution, etc |
2017 |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
1 electronic resource (174 p.) |
| 506 0# - RESTRICTIONS ON ACCESS NOTE |
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| Terms governing access |
Open Access |
| Source of term |
star |
| Standardized terminology for access restriction |
Unrestricted online access |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc |
It is now well appreciated that the immune system, in addition to its traditional role in defending the organism against pathogens, communicate in a well-organized fashion with the brain to maintain homeostasis and regulate a set of neural functions. Perturbation in this brain-immune interactions due to inflammatory responses may lead to psychiatric and neurological disorders. Microglia are one of the essential cells involved in the brain-immune interactions. Microglial cells are now not simply regarded as resident tissue macrophages in the brain. These cells are derived from myeloid progenitor cells in the yolk sac in early gestation, travel to the brain parenchyma and interact actively with neurons during the critical period of neurogenesis. Microglia provide a trophic support to developing neurons and take part in the neural wiring through the activity-dependent synapse elimination via direct neuron-microglia interactions. Altered microglial functions including changes in the gene expression due to early life inflammatory events or psychological and environmental stressors can be causally related to neurodevelopmental diseases and mental health disorders. This type of alterations in the neural functions can occur in the absence of infiltration of inflammatory cells in the brain parenchyma or leptomeninges. In this sense, the pathogenetic state underlying a significant part of psychiatric and neurological diseases may be similar to "para-inflammation", an intermediate state between homeostatic and classical inflammatory states as defined by Ruslan Medzhitov (Nature 454:428-35, 2008). Therefore, it is important to study how systemic inflammation affects brain health and how local peripheral inflammation induces changes in the brain microenvironment. Chronic pain is also induced by disturbance in otherwise well-organized multisystem interplay comprising of reciprocal neural, endocrine and immune interactions. Especially, early-life insults including exposure to immune challenges can alter the neuroanatomical components of nociception, which induces altered pain response later in life. Recently the discrete roles of microglia and blood monocyte-derived macrophages are being defined. The distinction may be further highlighted by disorders in which the brain parenchymal tissue is damaged. Therefore, studies investigating the dynamics of immune cells in traumatic brain injury and neurotropic viral infections including human immunodeficiency virus, etc. as well as neurodegenerative diseases such as amyotrophic lateral sclerosis are promising to clarify the interplay between the central nervous and immune systems. The understanding of the histological architecture providing the infrastructure of such neuro-immune interplay is also essential. This Frontiers research topic brings together fourteen articles and aims to create a platform for researchers in the field of psychoneuroimmunology to share the recent theories, hypotheses and future perspectives regarding open questions on the mechanisms of cell-cell interactions with chemical mediators among the nervous, immune and endocrine systems. We hope that this platform would reveal the relevance of the studies on multisystem interactions to enhance the understanding of the mechanisms underlying a wide variety of neurological and psychiatric disorders. |
| 540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE |
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| Terms governing use and reproduction |
Creative Commons |
| -- |
https://creativecommons.org/licenses/by/4.0/ |
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cc |
| -- |
https://creativecommons.org/licenses/by/4.0/ |
| 546 ## - LANGUAGE NOTE |
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| Language note |
English |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
brain-immune interaction |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
fatigue |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
pain |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
HIV |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
neuroinflammation |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
traumatic brain injury |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
depression |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
microglia |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
amyotrophic lateral sclerosis |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
autism |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Ihssane Zouikr |
| Relator code |
auth |
| 9 (RLIN) |
1621193 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Sanae Hasegawa-Ishii |
| Relator code |
auth |
| 9 (RLIN) |
1621194 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Host name |
www.oapen.org |
| Uniform Resource Identifier |
<a href="https://www.frontiersin.org/research-topics/4387/neuroimmune-interface-in-health-and-diseases">https://www.frontiersin.org/research-topics/4387/neuroimmune-interface-in-health-and-diseases</a> |
| -- |
0 |
| Public note |
DOAB: download the publication |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Host name |
www.oapen.org |
| Uniform Resource Identifier |
<a href="https://directory.doabooks.org/handle/20.500.12854/54505">https://directory.doabooks.org/handle/20.500.12854/54505</a> |
| -- |
0 |
| Public note |
DOAB: description of the publication |
