MARC details
| 000 -LEADER |
|---|
| fixed length control field |
03246naaaa2200361uu 4500 |
| 001 - CONTROL NUMBER |
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| control field |
https://directory.doabooks.org/handle/20.500.12854/44556 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20220714193839.0 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
978-2-88945-438-9 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9782889454389 |
| 024 7# - OTHER STANDARD IDENTIFIER |
|---|
| Standard number or code |
10.3389/978-2-88945-438-9 |
| Terms of availability |
doi |
| 041 0# - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
English |
| 042 ## - AUTHENTICATION CODE |
|---|
| Authentication code |
dc |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
S |
| Relator code |
auth |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Data-Based Radiation Oncology - Design of Clinical Trials |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
|---|
| Name of publisher, distributor, etc |
Frontiers Media SA |
| Date of publication, distribution, etc |
2018 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
1 electronic resource (109 p.) |
| 506 0# - RESTRICTIONS ON ACCESS NOTE |
|---|
| Terms governing access |
Open Access |
| Source of term |
star |
| Standardized terminology for access restriction |
Unrestricted online access |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc |
In radiation oncology as in many other specialties clinical trials are essential to investigate new therapy approaches. Usually, preparation for a prospective clinical trial is extremely time consuming until ethics approval is obtained. To test a new treatment usually many years pass before it can be implemented in the routine care. During that time, already new interventions emerge, new drugs appear on the market, technical & physical innovations are being implemented, novel biology driven concepts are translated into clinical approaches while we are still investigating the ones from years ago. Another problem is associated with molecular diagnostics and the growing amount of tumor specific biomarkers which allows for a better stratification of patient subgroups. On the other side, this may result in a much longer time for patient recruiting and consequently in larger multicenter trials. Moreover, all of the relevant data must be readily available for treatment decision making, treatment as well as follow-up, and ultimately for trial evaluation. This challenges even more for agreed standards in data acquisition, quality and management. How could we change the way currently clinical trials are performed in a way they are safe and ethically justifiable and speed up the initiation process, so we can provide new and better treatments faster for our patients? Further, while we rely on various quantitative information handling distributed, large heterogeneous amounts of data efficiently is very important. Thus data management becomes a strong focus. A good infrastructure helps to plan, tailor and conduct clinical trials in a way they are easy and quickly analyzable. In this research topic we want to discuss new ideas for intelligent trial designs and concepts for data management. |
| 540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE |
|---|
| Terms governing use and reproduction |
Creative Commons |
| -- |
https://creativecommons.org/licenses/by/4.0/ |
| -- |
cc |
| -- |
https://creativecommons.org/licenses/by/4.0/ |
| 546 ## - LANGUAGE NOTE |
|---|
| Language note |
English |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Study Management |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Clinical trials |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Data Collection |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Radiation Oncology |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Clinical Study design |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Kerstin A. Kessel |
| Relator code |
auth |
| 9 (RLIN) |
1620219 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Fridtjof Nuesslin |
| Relator code |
auth |
| 9 (RLIN) |
1620220 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Bhadrasain Vikram |
| Relator code |
auth |
| 9 (RLIN) |
1620221 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Anne W. Lee |
| Relator code |
auth |
| 9 (RLIN) |
1620222 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Stephanie E. Combs |
| Relator code |
auth |
| 9 (RLIN) |
1620223 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Host name |
www.oapen.org |
| Uniform Resource Identifier |
<a href="https://www.frontiersin.org/research-topics/4727/data-based-radiation-oncology---design-of-clinical-trials">https://www.frontiersin.org/research-topics/4727/data-based-radiation-oncology---design-of-clinical-trials</a> |
| -- |
0 |
| Public note |
DOAB: download the publication |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Host name |
www.oapen.org |
| Uniform Resource Identifier |
<a href="https://directory.doabooks.org/handle/20.500.12854/44556">https://directory.doabooks.org/handle/20.500.12854/44556</a> |
| -- |
0 |
| Public note |
DOAB: description of the publication |
