MARC details
| 000 -LEADER |
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| fixed length control field |
04504naaaa2201057uu 4500 |
| 001 - CONTROL NUMBER |
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| control field |
https://directory.doabooks.org/handle/20.500.12854/68973 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20220714191740.0 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
books978-3-03936-283-7 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9783039362820 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9783039362837 |
| 024 7# - OTHER STANDARD IDENTIFIER |
|---|
| Standard number or code |
10.3390/books978-3-03936-283-7 |
| Terms of availability |
doi |
| 041 0# - LANGUAGE CODE |
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| Language code of text/sound track or separate title |
English |
| 042 ## - AUTHENTICATION CODE |
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| Authentication code |
dc |
| 072 #7 - SUBJECT CATEGORY CODE |
|---|
| Subject category code |
GP |
| Source |
bicssc |
| 072 #7 - SUBJECT CATEGORY CODE |
|---|
| Subject category code |
PS |
| Source |
bicssc |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Di Meo, Sergio |
| Relator code |
edt |
| 9 (RLIN) |
1615236 |
| 245 10 - TITLE STATEMENT |
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| Title |
Physiological and Pathological Role of ROS: Benefits and Limitations of Antioxidant Treatment |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
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| Place of publication, distribution, etc |
Basel, Switzerland |
| Name of publisher, distributor, etc |
MDPI - Multidisciplinary Digital Publishing Institute |
| Date of publication, distribution, etc |
2020 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
1 electronic resource (236 p.) |
| 506 0# - RESTRICTIONS ON ACCESS NOTE |
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| Terms governing access |
Open Access |
| Source of term |
star |
| Standardized terminology for access restriction |
Unrestricted online access |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc |
ROS were long considered one of the key players in tissue injury. Indeed, overproduction of ROS results in oxidative stress, a process leading to the development of many pathological conditions. For the treatment of these conditions, the use of antioxidants was proposed. Over time, it was shown that ROS at low concentrations act as signaling molecules, leading to the regulation of physiological functions. Moreover, several interventions that increase ROS generation activate stress-adaptive responses that extend the lifespan. It was also shown that excessive use of antioxidants can counter the beneficial effects of ROS. Currently, much progress has been made in understanding the role of ROS in human diseases and aging, as well as in the regulation of physiological functions, and in identifying the signaling pathways involved in ROS. However, much remains to be understood about the mutual interactions among signaling pathways underlying organisms' adaptive responses, their modifications (which occur during aging), and some disease states. The aim of this Special Issue is to underline the effects of ROS production and antioxidant treatment in living organisms, focusing on their impact on health, disease, and aging. |
| 540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE |
|---|
| Terms governing use and reproduction |
Creative Commons |
| -- |
https://creativecommons.org/licenses/by/4.0/ |
| -- |
cc |
| -- |
https://creativecommons.org/licenses/by/4.0/ |
| 546 ## - LANGUAGE NOTE |
|---|
| Language note |
English |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Research & information: general |
| Source of heading or term |
bicssc |
| 9 (RLIN) |
928234 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Biology, life sciences |
| Source of heading or term |
bicssc |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
CTCL |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
apoptosis |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
cell viability |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
c-FLIP |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
XIAP |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
artemisinin |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
SH-SY5Y cells |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
hippocampal neurons |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
H2O2 |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
AMPK pathway |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
atherosclerosis |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
sphingomyelin synthase 2 |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
endothelial dysfunction |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
endoplasmic reticulum stress |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
β-catenin |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
insulin resistance |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
cancer |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
cardiovascular disease |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
neurodegenerative disorders |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
exercise |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
mitochondria |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
oxidative stress |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
PGC-1 |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Nrf2 |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
UCPs |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
ROS |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
light |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
DNA damage |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
evolution |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
D-box |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
cavefish |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Spalax |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
trimethylamine N-oxide |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
cardiomyocytes |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
cardiotoxicity |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
mitochondrial membrane potential |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
CORM-2 |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
NADPH oxidase |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
AP-1 |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
HO-1 |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Renal cell carcinoma (RCC) |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
reactive oxygen species (ROS) |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
glutathione (GSH) metabolism |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
cancer therapy |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
clear cell RCC |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
papillary RCC |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
chromophobe RCC |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
sarcopenia |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
reactive oxygen species |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
redox signaling |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
antioxidant supplementation |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
protein aggregation |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
redox |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
proteinopathy |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
peroxiredoxins |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
tumorigenesis |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
ROS scavengers |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
n/a |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Venditti, Paola |
| Relator code |
edt |
| 9 (RLIN) |
1615237 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Napolitano, Gaetana |
| Relator code |
edt |
| 9 (RLIN) |
1615238 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Di Meo, Sergio |
| Relator code |
oth |
| 9 (RLIN) |
1615236 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Venditti, Paola |
| Relator code |
oth |
| 9 (RLIN) |
1615237 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Napolitano, Gaetana |
| Relator code |
oth |
| 9 (RLIN) |
1615238 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Host name |
www.oapen.org |
| Uniform Resource Identifier |
<a href="https://mdpi.com/books/pdfview/book/2741">https://mdpi.com/books/pdfview/book/2741</a> |
| -- |
0 |
| Public note |
DOAB: download the publication |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Host name |
www.oapen.org |
| Uniform Resource Identifier |
<a href="https://directory.doabooks.org/handle/20.500.12854/68973">https://directory.doabooks.org/handle/20.500.12854/68973</a> |
| -- |
0 |
| Public note |
DOAB: description of the publication |
