MARC details
| 000 -LEADER |
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| fixed length control field |
04163naaaa2200841uu 4500 |
| 001 - CONTROL NUMBER |
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| control field |
https://directory.doabooks.org/handle/20.500.12854/42687 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20220714190621.0 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
books978-3-03928-317-0 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9783039283170 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9783039283163 |
| 024 7# - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.3390/books978-3-03928-317-0 |
| Terms of availability |
doi |
| 041 0# - LANGUAGE CODE |
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| Language code of text/sound track or separate title |
English |
| 042 ## - AUTHENTICATION CODE |
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| Authentication code |
dc |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
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| Personal name |
Rauter, Amélia Pilar |
| Relator code |
auth |
| 9 (RLIN) |
1611767 |
| 245 10 - TITLE STATEMENT |
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| Title |
Carbohydrates 2018 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
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| Name of publisher, distributor, etc |
MDPI - Multidisciplinary Digital Publishing Institute |
| Date of publication, distribution, etc |
2020 |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
1 electronic resource (172 p.) |
| 506 0# - RESTRICTIONS ON ACCESS NOTE |
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| Terms governing access |
Open Access |
| Source of term |
star |
| Standardized terminology for access restriction |
Unrestricted online access |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc |
This book contains original papers and reviews on carbohydrate research in medicine, authored by participants of the 29th International Carbohydrate Symposium, where this topic had a special emphasis. The focus on biological events involving carbohydrates and glycoconjugates has delivered reliable approaches for disease treatment and diagnosis. Research on carbohydrate-based compounds for therapeutic applications is illustrated in various contributions, namely those covering the development of novel agents against Alzheimer's disease, e.g. the neuroprotective C-glucosylated flavones and the isonucleoside-based cholinesterase inhibitors. New imino sugar glucosidase inhibitors are also disclosed, a class of compounds with potential for diabetes, Gaucher disease or cancer treatment. Also the development of a useful synthetic method towards multivalent glycoclusters of biomedical interest is here highlighted. The relevance of glycomimetics in drug discovery and the progress on carbohydrates in early diagnosis and cancer treatment are reviewed. Noteworthy is the chitosan-based delivery system for drug oral administration, a new biomaterial-based approach to improve bioavailability. Another study on the conformation of Streptococcus capsular polysaccharide backbones by molecular modelling provides useful information for bacterial immunotherapeutic approaches. All original contributions and reviews clearly demonstrate the potential of glycosciences for innovation in medicinal (glyco)chemistry and pharmaceutical research. |
| 540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE |
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| Terms governing use and reproduction |
Creative Commons |
| -- |
https://creativecommons.org/licenses/by-nc-nd/4.0/ |
| -- |
cc |
| -- |
https://creativecommons.org/licenses/by-nc-nd/4.0/ |
| 546 ## - LANGUAGE NOTE |
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| Language note |
English |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
chitosan |
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cancer treatment |
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n/a |
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theobromine |
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multivalent |
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carbohydrate |
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glycomimetic |
| 653 ## - INDEX TERM--UNCONTROLLED |
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capsular polysaccharide |
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isonucleosides |
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carbohydrate-based antitumor vaccines |
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carbohydrate antigen |
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sugars |
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Alzheimer's disease |
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conjugate vaccines |
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drug development |
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microparticles |
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cancer diagnosis |
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polyhydroxypiperidines |
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Streptococcus pneumoniae |
| 653 ## - INDEX TERM--UNCONTROLLED |
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iminosugar |
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oral films |
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Group B Streptococcus |
| 653 ## - INDEX TERM--UNCONTROLLED |
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C-glucosyl flavonoids |
| 653 ## - INDEX TERM--UNCONTROLLED |
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glycosidase inhibition |
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polyhydroxyazepanes |
| 653 ## - INDEX TERM--UNCONTROLLED |
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carbohydrate antigens |
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binding affinity |
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A?1-42 |
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glucosidase inhibition |
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lectin |
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Mitsunobu reaction |
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Microwave reactions |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
chromen-4-ones |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
iminosugars |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
flavones |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
cholinesterase inhibitors |
| 653 ## - INDEX TERM--UNCONTROLLED |
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chemoselective |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
glycoclusters |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
lead optimization |
| 653 ## - INDEX TERM--UNCONTROLLED |
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PAMPA |
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oxime |
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| Uncontrolled term |
bioactive peptides |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
molecular modeling |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
buccal delivery |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
warburg effect |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
aminooxy |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
miglustat |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
miglitol |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Xavier, Nuno Manuel |
| Relator code |
auth |
| 9 (RLIN) |
1611768 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Host name |
www.oapen.org |
| Uniform Resource Identifier |
<a href="https://mdpi.com/books/pdfview/book/2135">https://mdpi.com/books/pdfview/book/2135</a> |
| -- |
0 |
| Public note |
DOAB: download the publication |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Host name |
www.oapen.org |
| Uniform Resource Identifier |
<a href="https://directory.doabooks.org/handle/20.500.12854/42687">https://directory.doabooks.org/handle/20.500.12854/42687</a> |
| -- |
0 |
| Public note |
DOAB: description of the publication |
