MARC details
| 000 -LEADER |
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| fixed length control field |
03940naaaa2200385uu 4500 |
| 001 - CONTROL NUMBER |
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| control field |
https://directory.doabooks.org/handle/20.500.12854/50091 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20220714185603.0 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
978-2-88919-962-4 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9782889199624 |
| 024 7# - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.3389/978-2-88919-962-4 |
| Terms of availability |
doi |
| 041 0# - LANGUAGE CODE |
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| Language code of text/sound track or separate title |
English |
| 042 ## - AUTHENTICATION CODE |
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| Authentication code |
dc |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
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| Personal name |
Margareta Nikolic |
| Relator code |
auth |
| 9 (RLIN) |
1608643 |
| 245 10 - TITLE STATEMENT |
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| Title |
In vivo Cell Biology of Cerebral Cortical Development and Its Related Neurological Disorders: Cellular Insights into Neurogenesis and Neuronal Migration |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
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| Name of publisher, distributor, etc |
Frontiers Media SA |
| Date of publication, distribution, etc |
2016 |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
1 electronic resource (268 p.) |
| 506 0# - RESTRICTIONS ON ACCESS NOTE |
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| Terms governing access |
Open Access |
| Source of term |
star |
| Standardized terminology for access restriction |
Unrestricted online access |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc |
The brain consists of a complex but precisely organized neural network, which provides the structural basis of higher order functions. Such a complex structure originates from a simple pseudostratified neuroepithelium. During the developing mammalian cerebral cortex, a cohort of neural progenitors, located near the ventricle, differentiates into neurons and exhibits multi-step modes of migration toward the pial surface. Tight regulation of neurogenesis and neuronal migration is essential for the determination of the neuron number in adult brains and the proper positioning of excitatory and inhibitory neurons in a specific layer, respectively. In addition, defects in neurogenesis and neuronal migration can cause several neurological disorders, such as microcephaly, periventricular heterotopia and lissencephaly. Recent advances in genetic approaches to study the developing cerebral cortex, as well as the use of a number of novel techniques, particularly in vivo electroporation and time-lapse analyses using explant slice cultures, have significantly increased our understanding of cortical development. These novel techniques have allowed for cell biological analyses of cerebral cortical development in vivo or ex vivo, showing that many cellular events, including endocytosis, cell adhesion, microtubule and actin cytoskeletal regulation, neurotransmitter release, stress response, the consequence of cellular crowding (physical force), dynamics of transcription factors, midbody release and polarity transition are required for neurogenesis and/or neuronal migration. The aim of this research topic is to highlight molecular and cellular mechanisms underlying cerebral cortical development and its related neurological disorders from the cell biological point of views, such as cell division, cell-cycle regulation, cytoskeletal organization, cell adhesion and membrane trafficking. The topic has been organized into three chapters: 1) neurogenesis and cell fate determination, 2) neuronal migration and 3) cortical development-related neurological disorders. We hope that the results and discussions contributed by all authors in this research topic will be broadly useful for further advances in basic research, as well as improvements in the etiology and care of patients suffering from neurological and psychiatric disorders. |
| 540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE |
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| Terms governing use and reproduction |
Creative Commons |
| -- |
https://creativecommons.org/licenses/by/4.0/ |
| -- |
cc |
| -- |
https://creativecommons.org/licenses/by/4.0/ |
| 546 ## - LANGUAGE NOTE |
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| Language note |
English |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Endocytosis |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Cell Cycle |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Periventricular heterotopia |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Lissencephaly |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
neuronal migration |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Cell Division |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Cytoskeleton |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Microcephaly |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Neurogenesis |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Cell Adhesion |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Takeshi Kawauchi |
| Relator code |
auth |
| 9 (RLIN) |
1608644 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Yoko Arai |
| Relator code |
auth |
| 9 (RLIN) |
1608645 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Host name |
www.oapen.org |
| Uniform Resource Identifier |
<a href="http://journal.frontiersin.org/researchtopic/2703/in-vivo-cell-biology-of-cerebral-cortical-development-and-its-related-neurological-disorders-cellula">http://journal.frontiersin.org/researchtopic/2703/in-vivo-cell-biology-of-cerebral-cortical-development-and-its-related-neurological-disorders-cellula</a> |
| -- |
0 |
| Public note |
DOAB: download the publication |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Host name |
www.oapen.org |
| Uniform Resource Identifier |
<a href="https://directory.doabooks.org/handle/20.500.12854/50091">https://directory.doabooks.org/handle/20.500.12854/50091</a> |
| -- |
0 |
| Public note |
DOAB: description of the publication |
