Rheumatoid Arthritis Therapy Reappraisal : Strategies, Opportunities and Challenges (Record no. 3001680)

MARC details
000 -LEADER
fixed length control field 05034naaaa2201225uu 4500
001 - CONTROL NUMBER
control field https://directory.doabooks.org/handle/20.500.12854/69097
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20220714181505.0
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number books978-3-03943-091-8
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9783039430901
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9783039430918
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.3390/books978-3-03943-091-8
Terms of availability doi
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title English
042 ## - AUTHENTICATION CODE
Authentication code dc
072 #7 - SUBJECT CATEGORY CODE
Subject category code M
Source bicssc
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Müller, Rüdiger
Relator code edt
9 (RLIN) 1599056
245 10 - TITLE STATEMENT
Title Rheumatoid Arthritis Therapy Reappraisal : Strategies, Opportunities and Challenges
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication, distribution, etc Basel, Switzerland
Name of publisher, distributor, etc MDPI - Multidisciplinary Digital Publishing Institute
Date of publication, distribution, etc 2020
300 ## - PHYSICAL DESCRIPTION
Extent 1 electronic resource (260 p.)
506 0# - RESTRICTIONS ON ACCESS NOTE
Terms governing access Open Access
Source of term star
Standardized terminology for access restriction Unrestricted online access
520 ## - SUMMARY, ETC.
Summary, etc Rheumatoid Arthritis (RA) is a chronic inflammatory disease leading to joint inflammation and destruction. Treatment of RA includes the use of conventional (cs), biologic (b) disease-modifying anti-rheumatic drugs (DMARDs), and oral or intraarticular (IA) glucocorticoids (GCs). All different classes of drugs have shown to halt disease progression in clinical studies. In real life, a physician has more options than just adding or switching to a new ts/bDMARD if any kind of DMARDs has failed. They can modify or optimize the therapy with concomitant csDMARDs, and oral or IA-GC can be added to the treatment regimen. The EULAR states that therapeutic adjustment including the "optimization of csDMARDs dose or route of administration or intra-articular injections of GCs" is recommended. Thus, a new therapeutic agent can be embedded in a whole strategy with parallel optimization of the csDMARD and GC treatment. The idea of treating to target (T2T) for the treatment of RA patients has been around since the late 1990s. Many clinical studies (Ticora, BsSt, Camera) have demonstrated the superiority of a T2T approach. When I talk to physicians, I understand that most of them only rarely inject joints with GC. Therefore, I would like to create an issue on the T2T approach in reality including primary data, reviews, and real-life data demonstrating the general opinion and execution of T2T in treating RA.
540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE
Terms governing use and reproduction Creative Commons
-- https://creativecommons.org/licenses/by/4.0/
-- cc
-- https://creativecommons.org/licenses/by/4.0/
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Language note English
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Topical term or geographic name as entry element Medicine
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700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Müller, Rüdiger
Relator code oth
9 (RLIN) 1599056
856 40 - ELECTRONIC LOCATION AND ACCESS
Host name www.oapen.org
Uniform Resource Identifier <a href="https://mdpi.com/books/pdfview/book/2866">https://mdpi.com/books/pdfview/book/2866</a>
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Public note DOAB: download the publication
856 40 - ELECTRONIC LOCATION AND ACCESS
Host name www.oapen.org
Uniform Resource Identifier <a href="https://directory.doabooks.org/handle/20.500.12854/69097">https://directory.doabooks.org/handle/20.500.12854/69097</a>
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Public note DOAB: description of the publication
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