MARC details
| 000 -LEADER |
|---|
| fixed length control field |
03239naaaa2200553uu 4500 |
| 001 - CONTROL NUMBER |
|---|
| control field |
https://directory.doabooks.org/handle/20.500.12854/68296 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20220714181029.0 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
books978-3-03943-812-9 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9783039438112 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9783039438129 |
| 024 7# - OTHER STANDARD IDENTIFIER |
|---|
| Standard number or code |
10.3390/books978-3-03943-812-9 |
| Terms of availability |
doi |
| 041 0# - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
English |
| 042 ## - AUTHENTICATION CODE |
|---|
| Authentication code |
dc |
| 072 #7 - SUBJECT CATEGORY CODE |
|---|
| Subject category code |
M |
| Source |
bicssc |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Nopoulos, Peggy C. |
| Relator code |
edt |
| 9 (RLIN) |
1598029 |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Juvenile Onset Huntington's Disease |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
|---|
| Place of publication, distribution, etc |
Basel, Switzerland |
| Name of publisher, distributor, etc |
MDPI - Multidisciplinary Digital Publishing Institute |
| Date of publication, distribution, etc |
2021 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
1 electronic resource (102 p.) |
| 506 0# - RESTRICTIONS ON ACCESS NOTE |
|---|
| Terms governing access |
Open Access |
| Source of term |
star |
| Standardized terminology for access restriction |
Unrestricted online access |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc |
The Special Issue "Juvenile Onset Huntington's Disease" highlights the growing interest in understanding the unique aspects of this ultra-rare disorder. After decades of research, gene therapy trials are underway for Adult Onset Huntington's Disease (AOHD). However, patients with Juvenile Onset Huntington's Disease (JOHD) are often excluded from these efforts, leaving many questions regarding its phenomenology. The current issue includes seven articles spanning work on the difficult emotional experiences of parents of children with JOHD; a review of the clinical manifestations of JOHD; behavioral issues in JOHD; CAG repeat and age of motor onset; autonomic nervous system dysfunction; and abnormality in MRI metabolic markers. Finally, a review of the therapeutic advances is included, highlighting future possibilities of clinical trials in JOHD subjects. The HD community-patients, family members at-risk for HD, caregivers, health-care professionals and scientists-is keen on expanding our understanding of JOHD. In the flurry of research on AOHD, those with JOHD were seemingly 'left behind.' The study of patients who are afflicted early in life with HD has become imperative, with this Special Issue representing just the beginning of the required effort to address this urgent need. |
| 540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE |
|---|
| Terms governing use and reproduction |
Creative Commons |
| -- |
https://creativecommons.org/licenses/by/4.0/ |
| -- |
cc |
| -- |
https://creativecommons.org/licenses/by/4.0/ |
| 546 ## - LANGUAGE NOTE |
|---|
| Language note |
English |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Medicine |
| Source of heading or term |
bicssc |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Huntington's disease |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
CAG repeat |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
mutant huntingtin (mHTT) |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
therapeutics |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
neurodegeneration |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
juvenile Huntington's disease |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
pediatric Huntington's disease |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
early-onset Huntington's disease |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
personal experiences |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
caregivers |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
case series |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
juvenile-onset Huntington's disease |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
T1-Rho |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
neuroimaging |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
behavioral regulation |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
executive function |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
trinucleotide repeat disorder |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
CAG |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
motor onset |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
juvenile-onset Huntington's Disease |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
autonomic |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
n/a |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Nopoulos, Peggy C. |
| Relator code |
oth |
| 9 (RLIN) |
1598029 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Host name |
www.oapen.org |
| Uniform Resource Identifier |
<a href="https://mdpi.com/books/pdfview/book/3306">https://mdpi.com/books/pdfview/book/3306</a> |
| -- |
0 |
| Public note |
DOAB: download the publication |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Host name |
www.oapen.org |
| Uniform Resource Identifier |
<a href="https://directory.doabooks.org/handle/20.500.12854/68296">https://directory.doabooks.org/handle/20.500.12854/68296</a> |
| -- |
0 |
| Public note |
DOAB: description of the publication |
