MARC details
000 -LEADER |
fixed length control field |
02852naaaa2200289uu 4500 |
001 - CONTROL NUMBER |
control field |
https://directory.doabooks.org/handle/20.500.12854/81832 |
005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20220714172315.0 |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
International Standard Book Number |
hepatocellularcarcinoma.2019 |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
International Standard Book Number |
9780994438188 |
024 7# - OTHER STANDARD IDENTIFIER |
Standard number or code |
10.15586/hepatocellularcarcinoma.2019 |
Terms of availability |
doi |
041 0# - LANGUAGE CODE |
Language code of text/sound track or separate title |
English |
042 ## - AUTHENTICATION CODE |
Authentication code |
dc |
072 #7 - SUBJECT CATEGORY CODE |
Subject category code |
MJCL |
Source |
bicssc |
100 1# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Tirnitz-Parker, Janina EE |
Relator code |
edt |
9 (RLIN) |
1587214 |
245 10 - TITLE STATEMENT |
Title |
Hepatocellular Carcinoma |
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
Place of publication, distribution, etc |
Australia |
Name of publisher, distributor, etc |
Exon Publications |
Date of publication, distribution, etc |
20191009 |
300 ## - PHYSICAL DESCRIPTION |
Extent |
1 electronic resource (165 p.) |
506 0# - RESTRICTIONS ON ACCESS NOTE |
Terms governing access |
Open Access |
Source of term |
star |
Standardized terminology for access restriction |
Unrestricted online access |
520 ## - SUMMARY, ETC. |
Summary, etc |
Hepatocellular carcinoma (HCC), the most common form of liver cancer, has become a major global health problem and is responsible for a steadily increasing number of cancer-related deaths. Although the risk factors for HCC development are well known and great advances have been made through HBV vaccinations, direct-acting antivirals for HCV treatment, and aflatoxin eradication programs, the overall incidence and mortality rates of HCC are still rising. To tackle the burden of HCC, it is essential to understand the principle molecular and cellular processes as well as fundamental clinical challenges. This book provides an overview on several important disease aspects. Chapter 1 reviews recent studies assessing the potential cellular origins of HCC. Chapter 2 describes the newly discovered regulatory roles of the tumor microenvironment on tumor growth and progression. Chapters 3 and 4 outline the most commonly used in vitro systems and animal models of chronic liver disease and HCC in detail. Chapter 5 provides an overview of metabolic reprogramming and dysregulation of lipid metabolism as a newly recognized hallmark of HCC. Chapter 6 details the currently accepted standards and challenges for the surgical management of HCC, while Chapter 7 provides an overview of the recent developments in the field of tyrosine kinase inhibitors. Chapter 8 discusses multidrug resistance to chemotherapy and potential approaches to overcome this clinical obstacle. The book, written by experts from several countries, addresses each topic in sophisticated detail. It will be a valuable resource for clinicians and investigators who are interested in HCC. |
540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE |
Terms governing use and reproduction |
Creative Commons |
-- |
https://creativecommons.org/licenses/by-nc-nd/4.0/ |
-- |
cc |
-- |
https://creativecommons.org/licenses/by-nc-nd/4.0/ |
546 ## - LANGUAGE NOTE |
Language note |
English |
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name as entry element |
MJCL |
Source of heading or term |
bicssc |
9 (RLIN) |
1587215 |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Hepatocellular Carcinoma |
700 1# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Tirnitz-Parker, Janina EE |
Relator code |
oth |
9 (RLIN) |
1587214 |
856 40 - ELECTRONIC LOCATION AND ACCESS |
Host name |
www.oapen.org |
Uniform Resource Identifier |
<a href="https://exonpublications.com/index.php/exon/issue/view/10">https://exonpublications.com/index.php/exon/issue/view/10</a> |
-- |
0 |
Public note |
DOAB: download the publication |
856 40 - ELECTRONIC LOCATION AND ACCESS |
Host name |
www.oapen.org |
Uniform Resource Identifier |
<a href="https://directory.doabooks.org/handle/20.500.12854/81832">https://directory.doabooks.org/handle/20.500.12854/81832</a> |
-- |
0 |
Public note |
DOAB: description of the publication |