MARC details
| 000 -LEADER |
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| fixed length control field |
04073naaaa2200781uu 4500 |
| 001 - CONTROL NUMBER |
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| control field |
https://directory.doabooks.org/handle/20.500.12854/76954 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20220714163558.0 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
books978-3-0365-2152-7 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9783036521510 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9783036521527 |
| 024 7# - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.3390/books978-3-0365-2152-7 |
| Terms of availability |
doi |
| 041 0# - LANGUAGE CODE |
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| Language code of text/sound track or separate title |
English |
| 042 ## - AUTHENTICATION CODE |
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| Authentication code |
dc |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
GP |
| Source |
bicssc |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
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| Personal name |
Bruni, Francesco |
| Relator code |
edt |
| 9 (RLIN) |
1577016 |
| 245 10 - TITLE STATEMENT |
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| Title |
Mitochondria: From Physiology to Pathology |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
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| Place of publication, distribution, etc |
Basel, Switzerland |
| Name of publisher, distributor, etc |
MDPI - Multidisciplinary Digital Publishing Institute |
| Date of publication, distribution, etc |
2021 |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
1 electronic resource (196 p.) |
| 506 0# - RESTRICTIONS ON ACCESS NOTE |
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| Terms governing access |
Open Access |
| Source of term |
star |
| Standardized terminology for access restriction |
Unrestricted online access |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc |
Mitochondria play an increasingly central role in the context of cellular physiology. These organelles possess their own genome (mtDNA), which is functionally coordinated with the nuclear genome. Mitochondrial gene expression is mediated by molecular processes (replication, transcription, translation, and assembly of respiratory chain complexes) that all take place within the mitochondria. Several aspects of mtDNA expression have already been well characterized, but many more either are under debate or have yet to be discovered. Understanding the molecular processes occurring in mitochondria also has clinical relevance. Dysfunctions affecting these important metabolic 'hubs' are associated with a whole range of severe disorders, known as mitochondrial diseases. In recent years, significant progress has been made to understand the pathogenic mechanisms underlying mitochondrial dysfunction; however, to date, mitochondrial diseases are complex genetic disorders without any effective therapy. Current therapeutic strategies and clinical trials are aimed at mitigating clinical manifestations and slowing the disease progression to improve the quality of life of patients. The goal of the Special Issue 'Mitochondria: from Physiology to Pathology' published in Life (ISSN: 2075-1729) was to collect research and review articles covering the physiological and pathological aspects related to mtDNA maintenance and gene expression, mitochondrial biogenesis, protein import, organelle metabolism, and quality control. |
| 540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE |
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| Terms governing use and reproduction |
Creative Commons |
| -- |
https://creativecommons.org/licenses/by/4.0/ |
| -- |
cc |
| -- |
https://creativecommons.org/licenses/by/4.0/ |
| 546 ## - LANGUAGE NOTE |
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| Language note |
English |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Research & information: general |
| Source of heading or term |
bicssc |
| 9 (RLIN) |
928234 |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
atherosclerosis |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
carotid intima-media thickness |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
mitochondrial mutations |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
cardiovascular risk factors |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
mitochondria |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
mtDNA |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
cristae |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
mitochondrial fission |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
mitochondrial fusion |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
mitochondrial diseas |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
mitochondrial dynamics |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
mitoenergetics |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
mitosteroidogenesis |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
LH |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
cAMP |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Leydig cell |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
mitochondrial DNA segregation |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
heteroplasmy |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
selective elimination |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
mitophagy |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
mitochondrial engineered nucleases |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
kinases |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
phosphorylation |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
disease |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
PINK1 |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Parkinson's disease |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
mitochondria homeostasis |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Cterm |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
MELAS |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
transmitochondrial cybrids |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
aminoacyl-tRNA synthetases |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
LARS2 |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
mitochondrial disease |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
therapeutic peptides |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
FAD synthase |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
FAD1 |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
mitochondria localization |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Saccharomyces cerevisiae |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
mRNA |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
mitochondrial localization motif |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
n/a |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Bruni, Francesco |
| Relator code |
oth |
| 9 (RLIN) |
1577016 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Host name |
www.oapen.org |
| Uniform Resource Identifier |
<a href="https://mdpi.com/books/pdfview/book/4545">https://mdpi.com/books/pdfview/book/4545</a> |
| -- |
0 |
| Public note |
DOAB: download the publication |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Host name |
www.oapen.org |
| Uniform Resource Identifier |
<a href="https://directory.doabooks.org/handle/20.500.12854/76954">https://directory.doabooks.org/handle/20.500.12854/76954</a> |
| -- |
0 |
| Public note |
DOAB: description of the publication |
