MARC details
| 000 -LEADER |
|---|
| fixed length control field |
02329naaaa2200337uu 4500 |
| 001 - CONTROL NUMBER |
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| control field |
https://directory.doabooks.org/handle/20.500.12854/53224 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20220714161109.0 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
978-2-88945-484-6 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9782889454846 |
| 024 7# - OTHER STANDARD IDENTIFIER |
|---|
| Standard number or code |
10.3389/978-2-88945-484-6 |
| Terms of availability |
doi |
| 041 0# - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
English |
| 042 ## - AUTHENTICATION CODE |
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| Authentication code |
dc |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Lluis Fajas |
| Relator code |
auth |
| 9 (RLIN) |
1571985 |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Metabolic Adaptation to Cell Growth and Proliferation in Normal and Pathological Conditions |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
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| Name of publisher, distributor, etc |
Frontiers Media SA |
| Date of publication, distribution, etc |
2018 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
1 electronic resource (70 p.) |
| 506 0# - RESTRICTIONS ON ACCESS NOTE |
|---|
| Terms governing access |
Open Access |
| Source of term |
star |
| Standardized terminology for access restriction |
Unrestricted online access |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc |
Proliferating cells must adapt their metabolism to fulfill the increased requirements for energy demands and biosynthetic intermediates. This adaptation is particularly relevant in cancer, where sustained rapid proliferation combined with the harsh conditions of the tumor microenvironment represent a major metabolic challenge. Noteworthy, metabolic reprogramming is now considered one of the hallmarks of cancer. However, the one size fits all rarely applies to the metabolic rewiring occurring in cancer cells, which ultimately depends on the combination of several factors such as the tumor's origin, the specific genetic alterations and the surrounding microenvironment. In the present Research Topic, we compile a series of articles that discuss different metabolic adaptations that proliferating cells undergo to sustain growth and division, as well as the potential therapeutic window to treat certain pathologies, with a special focus on cancer. |
| 540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE |
|---|
| Terms governing use and reproduction |
Creative Commons |
| -- |
https://creativecommons.org/licenses/by/4.0/ |
| -- |
cc |
| -- |
https://creativecommons.org/licenses/by/4.0/ |
| 546 ## - LANGUAGE NOTE |
|---|
| Language note |
English |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
cancer metabolism |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
proliferation |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
mitochondria |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
lipogenesis |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
metabolic adaptation |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
obesity |
| 653 ## - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Warburg effect |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Albert Giralt |
| Relator code |
auth |
| 9 (RLIN) |
1571986 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Host name |
www.oapen.org |
| Uniform Resource Identifier |
<a href="https://www.frontiersin.org/research-topics/4124/metabolic-adaptation-to-cell-growth-and-proliferation-in-normal-and-pathological-conditions">https://www.frontiersin.org/research-topics/4124/metabolic-adaptation-to-cell-growth-and-proliferation-in-normal-and-pathological-conditions</a> |
| -- |
0 |
| Public note |
DOAB: download the publication |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Host name |
www.oapen.org |
| Uniform Resource Identifier |
<a href="https://directory.doabooks.org/handle/20.500.12854/53224">https://directory.doabooks.org/handle/20.500.12854/53224</a> |
| -- |
0 |
| Public note |
DOAB: description of the publication |
