Staphylococcal Infections (Host and Pathogenic Factors) (Record no. 2978442)

MARC details
000 -LEADER
fixed length control field 05422naaaa2201225uu 4500
001 - CONTROL NUMBER
control field https://directory.doabooks.org/handle/20.500.12854/76962
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20220714160818.0
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number books978-3-0365-1417-8
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9783036514185
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9783036514178
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.3390/books978-3-0365-1417-8
Terms of availability doi
041 0# - LANGUAGE CODE
Language code of text/sound track or separate title English
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Authentication code dc
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Subject category code GP
Source bicssc
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Subject category code PS
Source bicssc
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Adhikari, Rajan P.
Relator code edt
9 (RLIN) 1570978
245 10 - TITLE STATEMENT
Title Staphylococcal Infections (Host and Pathogenic Factors)
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication, distribution, etc Basel, Switzerland
Name of publisher, distributor, etc MDPI - Multidisciplinary Digital Publishing Institute
Date of publication, distribution, etc 2021
300 ## - PHYSICAL DESCRIPTION
Extent 1 electronic resource (226 p.)
506 0# - RESTRICTIONS ON ACCESS NOTE
Terms governing access Open Access
Source of term star
Standardized terminology for access restriction Unrestricted online access
520 ## - SUMMARY, ETC.
Summary, etc Although 30% of the healthy human population is colonized with various Staphylococcus species, some staphylococcal strains, referred to as opportunistic pathogens, can cause minor to life-threatening diseases. The pathogenicity of these bacteria depends on their virulence factors and the robustness of the regulatory networks expressing these virulence factors. Virulence factors of pathogenic Staphylococcus spp. consist of numerous toxins, enterotoxins (some of which act as superantigens), enzymes, and proteins (cytoplasmic, extracellular, and surface) that are regulated by two-component (TC) and quorum-sensing (QS) regulatory networks. To enter this niche, some other Staphylococcus species, such as Staphylococcus simulans, produce a potent endopeptidase called lysostaphin, which can inhibit the growth of pathogenic S. aureus. Some other Staphylococcus species produce autolysins and cationic peptides to win the intra- and inter-species competition. The outcome of this microbial invasion depends not only on pathogenic factors but also on the host's internal and external defense mechanisms, including a healthy skin microbiome. A healthy skin microbiome population can prevent colonization by other major pathogens. As normal host microflora, these commensals establish a complex relationship with the host as well as the surrounding microbial communities. This Special Issue of Microorganisms is focused on studies and recent advancements in our understanding of staphylococcal virulence mechanisms that enable Staphylococcus spp. either to successfully establish themselves as a colonizer or to overcome the host's defense system to cause infection along with our effort to make an anti-staphylococcal vaccine.
540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE
Terms governing use and reproduction Creative Commons
-- https://creativecommons.org/licenses/by/4.0/
-- cc
-- https://creativecommons.org/licenses/by/4.0/
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Language note English
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Research & information: general
Source of heading or term bicssc
9 (RLIN) 928234
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Biology, life sciences
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700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Adhikari, Rajan P.
Relator code oth
9 (RLIN) 1570978
856 40 - ELECTRONIC LOCATION AND ACCESS
Host name www.oapen.org
Uniform Resource Identifier <a href="https://mdpi.com/books/pdfview/book/4554">https://mdpi.com/books/pdfview/book/4554</a>
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Public note DOAB: download the publication
856 40 - ELECTRONIC LOCATION AND ACCESS
Host name www.oapen.org
Uniform Resource Identifier <a href="https://directory.doabooks.org/handle/20.500.12854/76962">https://directory.doabooks.org/handle/20.500.12854/76962</a>
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Public note DOAB: description of the publication
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