Babesia and Human Babesiosis

Montero, Estrella

Babesia and Human Babesiosis - Basel MDPI - Multidisciplinary Digital Publishing Institute 2022 - 1 electronic resource (294 p.)

Open Access

Babesiosis, caused by tick-transmitted intraerythrocytic parasites (Babesia spp.), occurs worldwide. The disease mainly affects livestock, but records of infections in humans are increasing, and the disease is considered to be emerging worldwide. This book provides a comprehensive and holistic view of Babesia species that can infect humans. Numerous experts analyze, in detail, basic aspects of the biology of Babesia, the pathology of the babesiosis highlighting the pathogenesis of babesiosis in sickle cell, the eco-epidemiology of tick vectors and the impact of climate change on them, the current status, and future prospects for laboratory diagnosis and measures to prevent transfusion transmission. The book also focused on unidentified Babesia parasites that continue to emerge, most likely from wildlife, for which neither tick vector species nor vertebrate reservoir host species are currently known. Lastly, current and new therapies for infected patients, in vitro and in vivo culture systems for antibabesial evaluation and measures to prevent infections are also considered.


Creative Commons


English

books978-3-0365-4471-7 9783036544724 9783036544717

10.3390/books978-3-0365-4471-7 doi


Medicine
Epidemiology & medical statistics

babesiosis Babesia microti Babesia duncani parasite therapy atovaquone endochin-like quinolones (ELQs) human babesiosis Nantucket Island epidemiology ecology human risk European babesiosis Babesia divergens Babesia venatorum Ixodes ricinus parasite identity clinical cases diagnosis treatment Babesia diversity phylogenetic analysis blood transfusion prevention screening aspartyl protease plasmepsin apicomplexa piroplasmida BmIPA48 BMR1_03g00960 piroplasmid rhoptry-associated protein-1 (pRAP-1) ticks Babesia sp. biological cycle experimental transmission experimental models Ixodes scapularis climate global warming Babesia sp. MO1 Babesia capreoli rap-1a ama-1 phylogeny sickle-cell anemia hemolysis haemoglobinopathies immunoepidemiology case surveillance therapeutic drugs peptidases antibody-based assays nucleic acid tests multiplex detection next generation sequencing glycosylphosphatidylinositol protein structure antigen host blood analysis fallow deer ixodid ticks piroplasm red deer Theileria Babesia bovis Babesia bigemina Colombia n/a in vitro culture erythrocytes DMEM-F12 virulence

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