Genetics of Alzheimer's Disease

Ibanez, Laura

Genetics of Alzheimer's Disease - Basel MDPI - Multidisciplinary Digital Publishing Institute 2022 - 1 electronic resource (146 p.)

Open Access

This special issue on the genetics of Alzheimer's disease was edited by Drs. Laura Ibanez and Justin Miller in 2021. It contains 10 original articles and reviews that help readers understand specific genetic contributions to Alzheimer's disease and how genetics will play a role in future Alzheimer's disease research.


Creative Commons


English

books978-3-0365-2932-5 9783036529325 9783036529332

10.3390/books978-3-0365-2932-5 doi


Medicine
Neurosciences

Alzheimer disease expression quantitative trait loci (eQTL) rare variants set-based eQTL SKAT-O pathways immune system inflammation ROSMAP ADNI complement complement receptor 1 clusterin late-onset Alzheimer's disease genetics neuroinflammation Alzheimer's disease cytokines and growth factors genome-wide association study (GWAS) Polygenic Risk Score (PRS)-based analysis TOMM40 gene RNA transcription pseudogene mitochondrial dysfunction ITIM ITAM SIGLEC14 SIGLEC5 copy number variation CNV GWAS long non-coding RNA biomarkers peripheral system amyloid β tau APOE TREM2 OMICS therapeutics pairwise feature correlation feature reduction machine learning n/a

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