Emotional Modulation of the Synapse
Christa McIntyre
Emotional Modulation of the Synapse - Frontiers Media SA 2015 - 1 electronic resource (135 p.)
Open Access
Highly emotional events tend to be well remembered. The adaptive value in this is clear - those events that have a bearing on survival should be stored for future use as long-term memories whereas memories of inconsequential events would not as likely contribute to future survival. Enduring changes in the structure and function of synapses, neural circuitry, and ultimately behavior, can be modulated by highly aversive or rewarding experiences. In the last decade, the convergence of cellular, molecular, and systems neuroscience has produced new insights into the biological mechanisms that determine whether a memory will be stored for the long-term or lost forever. This Research Topic brings together leading experts, who work at multiple levels of analysis, to reveal recent discoveries and concepts regarding the synaptic mechanisms of consolidation and extinction of emotionally arousing memories.
Creative Commons
English
978-2-88919-606-7 9782889196067
10.3389/978-2-88919-606-7 doi
Brain Stimulation Amygdala BDNF PDE4 reconsolidation Fear conditioning posttraumatic stress disorder ubiquitin-proteasome system CREB extinction Sleep gamma oscillations
Emotional Modulation of the Synapse - Frontiers Media SA 2015 - 1 electronic resource (135 p.)
Open Access
Highly emotional events tend to be well remembered. The adaptive value in this is clear - those events that have a bearing on survival should be stored for future use as long-term memories whereas memories of inconsequential events would not as likely contribute to future survival. Enduring changes in the structure and function of synapses, neural circuitry, and ultimately behavior, can be modulated by highly aversive or rewarding experiences. In the last decade, the convergence of cellular, molecular, and systems neuroscience has produced new insights into the biological mechanisms that determine whether a memory will be stored for the long-term or lost forever. This Research Topic brings together leading experts, who work at multiple levels of analysis, to reveal recent discoveries and concepts regarding the synaptic mechanisms of consolidation and extinction of emotionally arousing memories.
Creative Commons
English
978-2-88919-606-7 9782889196067
10.3389/978-2-88919-606-7 doi
Brain Stimulation Amygdala BDNF PDE4 reconsolidation Fear conditioning posttraumatic stress disorder ubiquitin-proteasome system CREB extinction Sleep gamma oscillations