From Basic Research to New Tools and Challenges for the Genotoxicity Testing of Nanomaterials
FESSARD, Valérie
From Basic Research to New Tools and Challenges for the Genotoxicity Testing of Nanomaterials - Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021 - 1 electronic resource (188 p.)
Open Access
This Special Issue presents studies on the genotoxicity of nanomaterials. Although nanomaterials provide multiple benefits in a wide range of applications, challenges remain in addressing strong concerns about their risks to the environment and human health. As a result of inconsistencies among published results and diverging conclusions, the understanding of nanomaterial exposure and toxicity remains unclear. Determining whether these materials cause DNA damage-the first step in carcinogenesis-must be a priority in testing. In this book, readers will find recent publications on the genotoxic response to a broad range of nanomaterials, the impact of physico-chemical characteristics, safe-by-design and new developed tools.
Creative Commons
English
books978-3-0365-0113-0 9783036501123 9783036501130
10.3390/books978-3-0365-0113-0 doi
Humanities
Social interaction
graphene oxide reduced graphene oxide micronucleus oxidative stress safer-by-design tungsten nanoparticles tritiated particles in vitro testing cytotoxicity micronuclei formation DNA damage epigenetics DNA methylation BEAS-2B cells. polystyrene nanoparticles nanoplastics genotoxicity Hs27 human fibroblasts comet assay FPG enzyme TiO2NP SiO2NP ZnONP CeO2NP AgNP multi-walled carbon nanotubes (MWCNT) titanium dioxide nanoparticles lincomycin human amniotic cells in vitro genotoxicity apoptosis nanotoxicology metal oxides high throughput screening micronucleus assay nanomaterial aluminum oral route gut liver V79 cells Hprt advanced in vitro model hepatotoxicity liver spheroids 3D culture HepG2 nongenotoxic silver nanoparticles genotoxic cytotoxic antioxidant activity silver ions Allium cepa metal/coating agent ratio n/a
From Basic Research to New Tools and Challenges for the Genotoxicity Testing of Nanomaterials - Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021 - 1 electronic resource (188 p.)
Open Access
This Special Issue presents studies on the genotoxicity of nanomaterials. Although nanomaterials provide multiple benefits in a wide range of applications, challenges remain in addressing strong concerns about their risks to the environment and human health. As a result of inconsistencies among published results and diverging conclusions, the understanding of nanomaterial exposure and toxicity remains unclear. Determining whether these materials cause DNA damage-the first step in carcinogenesis-must be a priority in testing. In this book, readers will find recent publications on the genotoxic response to a broad range of nanomaterials, the impact of physico-chemical characteristics, safe-by-design and new developed tools.
Creative Commons
English
books978-3-0365-0113-0 9783036501123 9783036501130
10.3390/books978-3-0365-0113-0 doi
Humanities
Social interaction
graphene oxide reduced graphene oxide micronucleus oxidative stress safer-by-design tungsten nanoparticles tritiated particles in vitro testing cytotoxicity micronuclei formation DNA damage epigenetics DNA methylation BEAS-2B cells. polystyrene nanoparticles nanoplastics genotoxicity Hs27 human fibroblasts comet assay FPG enzyme TiO2NP SiO2NP ZnONP CeO2NP AgNP multi-walled carbon nanotubes (MWCNT) titanium dioxide nanoparticles lincomycin human amniotic cells in vitro genotoxicity apoptosis nanotoxicology metal oxides high throughput screening micronucleus assay nanomaterial aluminum oral route gut liver V79 cells Hprt advanced in vitro model hepatotoxicity liver spheroids 3D culture HepG2 nongenotoxic silver nanoparticles genotoxic cytotoxic antioxidant activity silver ions Allium cepa metal/coating agent ratio n/a