Endometriosis Research : From Bench to Bedside
Laganà , Antonio Simone
Endometriosis Research : From Bench to Bedside - Basel MDPI - Multidisciplinary Digital Publishing Institute 2022 - 1 electronic resource (151 p.)
Open Access
Endometriosis is defined as the presence of endometrial-like endometrial cells, glands, and stroma outside the uterus, causing a strong inflammatory-like microenvironment in the affected tissue. The exact prevalence of endometriosis is unknown, but estimates range from 2%-10% of women of reproductive age, to 50% of infertile women. Its etiopathogenesis of endometriosis still remains controversial-immune, hormonal, genetic, and epigenetic factors may be all involved, and several theories have been proposed to explain it.This book aims to summarize recent ground-breaking studies that may open new scenarios and change the perspective of the topic, including cutting-edge elements about diagnosis, pharmacologic and surgical treatments, as well as basic/translational science (immunology, cell biology, genetics, and epigenetics) pieces of evidence, to unravel new pathways to follow for the future diagnosis and management of endometriosis, and to improve our current knowledge of its aetiology.
Creative Commons
English
books978-3-0365-2798-7 9783036527987 9783036527994
10.3390/books978-3-0365-2798-7 doi
Medicine
BTG1 endometriosis human endometrial stromal cells endometrium uterus purinergic signaling ATP pathogenesis genetics epigenetics immunology ion channels etiology CFTR aquaporin chloride channels biomarker angiogenesis cytokines urinary biomarkers genetic polymorphisms SNPs aetiology Mediterranean population Sardinian population peritoneal fluid microenvironment precision medicine
Endometriosis Research : From Bench to Bedside - Basel MDPI - Multidisciplinary Digital Publishing Institute 2022 - 1 electronic resource (151 p.)
Open Access
Endometriosis is defined as the presence of endometrial-like endometrial cells, glands, and stroma outside the uterus, causing a strong inflammatory-like microenvironment in the affected tissue. The exact prevalence of endometriosis is unknown, but estimates range from 2%-10% of women of reproductive age, to 50% of infertile women. Its etiopathogenesis of endometriosis still remains controversial-immune, hormonal, genetic, and epigenetic factors may be all involved, and several theories have been proposed to explain it.This book aims to summarize recent ground-breaking studies that may open new scenarios and change the perspective of the topic, including cutting-edge elements about diagnosis, pharmacologic and surgical treatments, as well as basic/translational science (immunology, cell biology, genetics, and epigenetics) pieces of evidence, to unravel new pathways to follow for the future diagnosis and management of endometriosis, and to improve our current knowledge of its aetiology.
Creative Commons
English
books978-3-0365-2798-7 9783036527987 9783036527994
10.3390/books978-3-0365-2798-7 doi
Medicine
BTG1 endometriosis human endometrial stromal cells endometrium uterus purinergic signaling ATP pathogenesis genetics epigenetics immunology ion channels etiology CFTR aquaporin chloride channels biomarker angiogenesis cytokines urinary biomarkers genetic polymorphisms SNPs aetiology Mediterranean population Sardinian population peritoneal fluid microenvironment precision medicine