Bioactive Compounds from Marine-Derived Aspergillus, Penicillium, Talaromyces and Trichoderma Species
Nicoletti, Rosario
Bioactive Compounds from Marine-Derived Aspergillus, Penicillium, Talaromyces and Trichoderma Species - MDPI - Multidisciplinary Digital Publishing Institute 2019 - 1 electronic resource (134 p.)
Open Access
The importance of bioactive natural compounds in pharmacology and other biotechnological fields has stimulated the scientific community to explore new environmental contexts and their associated microbial diversity. As the largest frontier in biological discovery, the sea represents a significant source of organisms producing novel secondary metabolites with interesting bioactivities. Of the available biological material, fungi have received increasing consideration, both due to their pervasive occurrence in varying habitats as well as their aptitude to develop symbiotic associations with higher organisms in numerous contexts. In many cases, fungal strains have been reported as the real producers of drugs originally extracted from marine plants and animals. Due to the constantly increasing number of marine-derived fungi yielding valuable bioactive products, it is now appropriate to present these findings to a recipient audience in a more organized form. This Special Issue of Marine Drugs, entitled "Bioactive Compounds from Marine-Derived Aspergillus, Penicillium, Talaromyces, and Trichoderma Species"" is specifically focused on a few genera of ascomycetous fungi which are widespread regarding marine contexts and are particularly inclined to establishing symbiotic relationships. For this project, we welcome submissions of full research papers, short notes, and review articles reporting the discovery and characterization of products showing antibiotic, antitumor, antiviral, insecticidal, antimalarial, antifouling, antioxidant, plant growth-promoting and/or resistance-inducing, as well as other less-exploited activities.
Creative Commons
English
books978-3-03897-981-4 9783038979807 9783038979814
10.3390/books978-3-03897-981-4 doi
antibacterial activity n/a Talaromyces purpurogenus lapatinib antibacterial hydroxypyrrolidine bis-indolyl benzenoids penitrem A cytotoxicities sesquiterpenoid secondary metabolites drug discovery sponge-associated fungus candidusin Penicillium sp. TJ403-1 coumarin gefitinib bioactive products Aspergillaceae indole-diterpenoids mangroves diterpenoid Penicillium raistrickii ECD calculations Talaromyces marine-derived fungi BK (Maxi-K) channel polyketides EGFR chromone aspetritone Aspergillus breviane spiroditerpenoid endophytic fungi cytotoxic cytotoxicity breast cancer mangrove endophytic fungus IDH1 inhibitory activity NMR data calculations antifungal activity Aspergillus candidus diastereomers TNF-? sterone Aspergillus clavatus HER2 thermo-change strategy
Bioactive Compounds from Marine-Derived Aspergillus, Penicillium, Talaromyces and Trichoderma Species - MDPI - Multidisciplinary Digital Publishing Institute 2019 - 1 electronic resource (134 p.)
Open Access
The importance of bioactive natural compounds in pharmacology and other biotechnological fields has stimulated the scientific community to explore new environmental contexts and their associated microbial diversity. As the largest frontier in biological discovery, the sea represents a significant source of organisms producing novel secondary metabolites with interesting bioactivities. Of the available biological material, fungi have received increasing consideration, both due to their pervasive occurrence in varying habitats as well as their aptitude to develop symbiotic associations with higher organisms in numerous contexts. In many cases, fungal strains have been reported as the real producers of drugs originally extracted from marine plants and animals. Due to the constantly increasing number of marine-derived fungi yielding valuable bioactive products, it is now appropriate to present these findings to a recipient audience in a more organized form. This Special Issue of Marine Drugs, entitled "Bioactive Compounds from Marine-Derived Aspergillus, Penicillium, Talaromyces, and Trichoderma Species"" is specifically focused on a few genera of ascomycetous fungi which are widespread regarding marine contexts and are particularly inclined to establishing symbiotic relationships. For this project, we welcome submissions of full research papers, short notes, and review articles reporting the discovery and characterization of products showing antibiotic, antitumor, antiviral, insecticidal, antimalarial, antifouling, antioxidant, plant growth-promoting and/or resistance-inducing, as well as other less-exploited activities.
Creative Commons
English
books978-3-03897-981-4 9783038979807 9783038979814
10.3390/books978-3-03897-981-4 doi
antibacterial activity n/a Talaromyces purpurogenus lapatinib antibacterial hydroxypyrrolidine bis-indolyl benzenoids penitrem A cytotoxicities sesquiterpenoid secondary metabolites drug discovery sponge-associated fungus candidusin Penicillium sp. TJ403-1 coumarin gefitinib bioactive products Aspergillaceae indole-diterpenoids mangroves diterpenoid Penicillium raistrickii ECD calculations Talaromyces marine-derived fungi BK (Maxi-K) channel polyketides EGFR chromone aspetritone Aspergillus breviane spiroditerpenoid endophytic fungi cytotoxic cytotoxicity breast cancer mangrove endophytic fungus IDH1 inhibitory activity NMR data calculations antifungal activity Aspergillus candidus diastereomers TNF-? sterone Aspergillus clavatus HER2 thermo-change strategy