The Application of Viruses to Biotechnology
Varanda, Carla
The Application of Viruses to Biotechnology - Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021 - 1 electronic resource (296 p.)
Open Access
Viruses are microscopic agents that exist worldwide and are present in humans, animals, plants, and other living organisms in which they can cause devastating diseases. However, the advances of biotechnology and next-generation sequencing technologies have accelerated novel virus discovery, identification, sequencing, and manipulation, showing that they present unique characteristics that place them as valuable tools for a wide variety of biotechnological applications. Many applications of viruses have been used for agricultural purposes, namely concerning plant breeding and plant protection. Nevertheless, it is interesting to mention that plants have also many advantages to be used in vaccine production, such as the low cost and low risks they entail, showing once more the versatility of the use of viruses in biotechnology. Although it will obviously never be ignored that viruses are responsible for devastating diseases, it is clear that the more they are studied, the more possibilities they offer to us. They are now on the front line of the most revolutionizing techniques in several fields, providing advances that would not be possible without their existence. In this book there are presented studies that demonstrate the work developed using viruses in biotechnology. These studies were brought by experts that focus on the development and applications of many viruses in several fields, such as agriculture, the pharmaceutical industry, and medicine.
Creative Commons
English
books978-3-0365-2538-9 9783036525396 9783036525389
10.3390/books978-3-0365-2538-9 doi
Technology: general issues
Bacteriophage Salmonella biocontrol comparative genomics phage diversity grapevine apple latent spherical virus vector virus-induced flowering reduced generation time breeding of grapevine virus elimination Newcastle disease virus reverse genetics vaccines infectious diseases cancer porcine epidemic diarrhea virus VLP chemokines pig vaccine SARS-CoV-2 COVID-19 phages CRISPR viruses prevention diagnosis treatment adeno-associated virus (AAV) vector jaagsiekte sheep retrovirus (JSRV) LTR enhancer transduction viral vaccines cancers COVID-19 vaccines self-replicating RNA vectors DNA-based vaccines RNA-based vaccines plant virus viroid viral vector virus-induced gene silencing (VIGS) CRISPR/Cas9 genome editing carotenoid biosynthesis circular RNA infectious bursal disease virus immunization recombinant Lactococcus lactis variant strain baculovirus insect cells bacmid Tn7 genome stability protein expression chikungunya virus VLPs bioreactor CRISPR/Cas systems viral vectors gene editing plant genome engineering viral resistance adeno-associated virus AAV cancer gene therapy prophage hydrothermal vent Hypnocyclicus thermotrophus lytic cassette Escherichia coli heterologous expression codon optimization codon harmonization expression vectors aspect ratio VNPs TMV PVX CPMV geminivirus theranostics CRISPR-cas9 clodronate macrophage gene therapy gene expression nanotechnology
The Application of Viruses to Biotechnology - Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021 - 1 electronic resource (296 p.)
Open Access
Viruses are microscopic agents that exist worldwide and are present in humans, animals, plants, and other living organisms in which they can cause devastating diseases. However, the advances of biotechnology and next-generation sequencing technologies have accelerated novel virus discovery, identification, sequencing, and manipulation, showing that they present unique characteristics that place them as valuable tools for a wide variety of biotechnological applications. Many applications of viruses have been used for agricultural purposes, namely concerning plant breeding and plant protection. Nevertheless, it is interesting to mention that plants have also many advantages to be used in vaccine production, such as the low cost and low risks they entail, showing once more the versatility of the use of viruses in biotechnology. Although it will obviously never be ignored that viruses are responsible for devastating diseases, it is clear that the more they are studied, the more possibilities they offer to us. They are now on the front line of the most revolutionizing techniques in several fields, providing advances that would not be possible without their existence. In this book there are presented studies that demonstrate the work developed using viruses in biotechnology. These studies were brought by experts that focus on the development and applications of many viruses in several fields, such as agriculture, the pharmaceutical industry, and medicine.
Creative Commons
English
books978-3-0365-2538-9 9783036525396 9783036525389
10.3390/books978-3-0365-2538-9 doi
Technology: general issues
Bacteriophage Salmonella biocontrol comparative genomics phage diversity grapevine apple latent spherical virus vector virus-induced flowering reduced generation time breeding of grapevine virus elimination Newcastle disease virus reverse genetics vaccines infectious diseases cancer porcine epidemic diarrhea virus VLP chemokines pig vaccine SARS-CoV-2 COVID-19 phages CRISPR viruses prevention diagnosis treatment adeno-associated virus (AAV) vector jaagsiekte sheep retrovirus (JSRV) LTR enhancer transduction viral vaccines cancers COVID-19 vaccines self-replicating RNA vectors DNA-based vaccines RNA-based vaccines plant virus viroid viral vector virus-induced gene silencing (VIGS) CRISPR/Cas9 genome editing carotenoid biosynthesis circular RNA infectious bursal disease virus immunization recombinant Lactococcus lactis variant strain baculovirus insect cells bacmid Tn7 genome stability protein expression chikungunya virus VLPs bioreactor CRISPR/Cas systems viral vectors gene editing plant genome engineering viral resistance adeno-associated virus AAV cancer gene therapy prophage hydrothermal vent Hypnocyclicus thermotrophus lytic cassette Escherichia coli heterologous expression codon optimization codon harmonization expression vectors aspect ratio VNPs TMV PVX CPMV geminivirus theranostics CRISPR-cas9 clodronate macrophage gene therapy gene expression nanotechnology