Immunohistochemical Expression
Caltabiano, Rosario
Immunohistochemical Expression - Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021 - 1 electronic resource (168 p.)
Open Access
Immunohistochemistry (IHC) is an ancillary method, widely used in pathologists' practice, that allows identifying diagnostic and prognostic/predictive of therapeutic response protein markers on tissue samples by the use of specific monoclonal antibodies and chromogenic substances that guarantee the visualization of an antibody-antigene binding complex under a light microscope [1]. Coon et al., in 1941 [2], first introduced the use of fluorochrome-conjugated antibodies in clinical practice. Since then, IHC has gone from being a useful tool for identifying the differentiation line of otherwise undifferentiated cells to a technique capable of providing not only diagnostic but also prognostic and predictive indications of responses to specific therapeutic options [1,3]. The abovementioned peculiarities have made IHC one of the most used ancillary methods in the histopathological approach to human neoplastic and non-neoplastic diseases [3-5]. This Special Issue contains 11 accepted papers that provide readers with a comprehensive update on current and future applications of IHC in medical practice.
Creative Commons
English
books978-3-0365-0401-8 9783036504001 9783036504018
10.3390/books978-3-0365-0401-8 doi
Medicine
training exercise NGAL VDR kidney heart immunohistochemistry ABCB5 uveal melanoma prognosis metastasis pericardium cytokeratin c-kit PDGFR initial lymphatics macroH2A prognostic factor SLC22A12 URAT1 hypouricemia uric acid transporters excretion fraction of uric acid Hsp27 Hsp60 Hsp70 Hsp90 molecular chaperone chaperonopathies thyroid follicular adenoma follicular carcinoma differential diagnosis carcinogenesis matrix metalloproteinases temporomandibular joint disorder temporomandibular joint DEN liver inflammation ultra-structural changes oxidative stress EGCG Vitamin D prostate cancer urinary tract malformations megacystis enteric nervous system outcome and prognosis WT1 human embryonal/fetal tissues neoplastic tissue n/a
Immunohistochemical Expression - Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021 - 1 electronic resource (168 p.)
Open Access
Immunohistochemistry (IHC) is an ancillary method, widely used in pathologists' practice, that allows identifying diagnostic and prognostic/predictive of therapeutic response protein markers on tissue samples by the use of specific monoclonal antibodies and chromogenic substances that guarantee the visualization of an antibody-antigene binding complex under a light microscope [1]. Coon et al., in 1941 [2], first introduced the use of fluorochrome-conjugated antibodies in clinical practice. Since then, IHC has gone from being a useful tool for identifying the differentiation line of otherwise undifferentiated cells to a technique capable of providing not only diagnostic but also prognostic and predictive indications of responses to specific therapeutic options [1,3]. The abovementioned peculiarities have made IHC one of the most used ancillary methods in the histopathological approach to human neoplastic and non-neoplastic diseases [3-5]. This Special Issue contains 11 accepted papers that provide readers with a comprehensive update on current and future applications of IHC in medical practice.
Creative Commons
English
books978-3-0365-0401-8 9783036504001 9783036504018
10.3390/books978-3-0365-0401-8 doi
Medicine
training exercise NGAL VDR kidney heart immunohistochemistry ABCB5 uveal melanoma prognosis metastasis pericardium cytokeratin c-kit PDGFR initial lymphatics macroH2A prognostic factor SLC22A12 URAT1 hypouricemia uric acid transporters excretion fraction of uric acid Hsp27 Hsp60 Hsp70 Hsp90 molecular chaperone chaperonopathies thyroid follicular adenoma follicular carcinoma differential diagnosis carcinogenesis matrix metalloproteinases temporomandibular joint disorder temporomandibular joint DEN liver inflammation ultra-structural changes oxidative stress EGCG Vitamin D prostate cancer urinary tract malformations megacystis enteric nervous system outcome and prognosis WT1 human embryonal/fetal tissues neoplastic tissue n/a