Toxicological Effects of Mycotoxins on Target Cells
Juan-García, Ana
Toxicological Effects of Mycotoxins on Target Cells - Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020 - 1 electronic resource (218 p.)
Open Access
Mycotoxins are a Public Health concern that in last year have reached the top 10 food and product hazard categories in the Rapid Alert System for Food and Feed (RASFF), with almost six hundred notifications. The toxicological effects of mycotoxins are evaluated through the extrapolation of results from in vivo and in vitro assays. Studies of mycotoxins' effects at the cellular level precede those in organs and systems. All these studies are key steps for risk assessment and following legislation for mycotoxins. This Special Issue of Toxins comprises 10 original contributions and two reviews. The Issue reports new findings regarding toxic mechanisms, the use of innovative techniques to study the potential toxicity of mycotoxins not only individually but in combination, reflecting a real scenario according to current studies of mycotoxins.
Creative Commons
English
books978-3-03936-927-0 9783039369263 9783039369270
10.3390/books978-3-03936-927-0 doi
Medicine
Destruxin A Bombyx mori binding protein BmTudor-sn Bm12 cell Ochratoxin A (OTA) human Stem Cells mycotoxins cells cytotoxicity cell culture T-2 toxin HT-2 toxin apoptosis autophagy endophyte fungi neurotoxin lolitrems ochratoxin A beauvericin mixtures HepG2 cells genotoxicity cell cycle Fusarium Aspergillus Penicillium Alternaria emerging mycotoxin in vitro IPEC-J2 occurrence data trichothecene biosynthetic pathway acetyltransferase deacetylase deoxynivalenol 3-acetyldeoxynivalenol isotrichodermol isotrichodermin differentiated Caco-2 cells cell apoptosis transcriptome analysis hepatocyte chicken acute toxicity combined toxicity cell protection silibinin in silico prediction co-culture models mycotoxin interaction Loewe additivity combination index isobologram Chou-Talalay method MixLow IPEC-J2 cells RNA-seq inflammation MAPKs n/a
Toxicological Effects of Mycotoxins on Target Cells - Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020 - 1 electronic resource (218 p.)
Open Access
Mycotoxins are a Public Health concern that in last year have reached the top 10 food and product hazard categories in the Rapid Alert System for Food and Feed (RASFF), with almost six hundred notifications. The toxicological effects of mycotoxins are evaluated through the extrapolation of results from in vivo and in vitro assays. Studies of mycotoxins' effects at the cellular level precede those in organs and systems. All these studies are key steps for risk assessment and following legislation for mycotoxins. This Special Issue of Toxins comprises 10 original contributions and two reviews. The Issue reports new findings regarding toxic mechanisms, the use of innovative techniques to study the potential toxicity of mycotoxins not only individually but in combination, reflecting a real scenario according to current studies of mycotoxins.
Creative Commons
English
books978-3-03936-927-0 9783039369263 9783039369270
10.3390/books978-3-03936-927-0 doi
Medicine
Destruxin A Bombyx mori binding protein BmTudor-sn Bm12 cell Ochratoxin A (OTA) human Stem Cells mycotoxins cells cytotoxicity cell culture T-2 toxin HT-2 toxin apoptosis autophagy endophyte fungi neurotoxin lolitrems ochratoxin A beauvericin mixtures HepG2 cells genotoxicity cell cycle Fusarium Aspergillus Penicillium Alternaria emerging mycotoxin in vitro IPEC-J2 occurrence data trichothecene biosynthetic pathway acetyltransferase deacetylase deoxynivalenol 3-acetyldeoxynivalenol isotrichodermol isotrichodermin differentiated Caco-2 cells cell apoptosis transcriptome analysis hepatocyte chicken acute toxicity combined toxicity cell protection silibinin in silico prediction co-culture models mycotoxin interaction Loewe additivity combination index isobologram Chou-Talalay method MixLow IPEC-J2 cells RNA-seq inflammation MAPKs n/a