Functional Polymers as Innovative Tools in the Delivery of Antimicrobial Agents
Spizzirri, Umile Gianfranco
Functional Polymers as Innovative Tools in the Delivery of Antimicrobial Agents - Basel MDPI - Multidisciplinary Digital Publishing Institute 2022 - 1 electronic resource (222 p.)
Open Access
This Special Issue explored different topics concerning recent progress in the synthesis and characterization of suitable innovative macromolecular systems, proposed as carriers of specific antimicrobial molecules, to be employed in the biomedical and pharmaceutical fields. Many infectious diseases are induced by omnipresent micro-organisms, including bacteria, viruses, protozoa, fungi, and algae, and, consequently, are very common, accounting for a significant share of the global disease burden. Unfortunately, antimicrobial resistance, adverse effects, and the high cost of antimicrobials are crucial health challenges worldwide. One of the common efforts in addressing this issue lies in improving the existing antimicrobial delivery systems. In this regard, nanoparticles as well as three-dimensional hydrophilic systems represent valuable tools able to ensure excellent performances. Biocompatible polymeric particles, entrapping these bioactive molecules, are capable of releasing them over a desired period of time, thereby decreasing the frequency of their administration. At the same time, these systems are able to protect antimicrobial drugs from degradation, enhancing their bioavailability. This Special Issue serves to highlight and capture the contemporary progress recorded in this field.
Creative Commons
English
books978-3-0365-3622-4 9783036536217 9783036536224
10.3390/books978-3-0365-3622-4 doi
Research & information: general
film nanocomposite essential oil supercritical CO2 long-term package hybrid nanoparticles biocompatible polymer antimicrobial amphiphiles dynamic light scattering scanning electron microscopy cell viability from counting of colony-forming unities antimicrobial activity of nanoparticles Escherichia coli Staphylococcus aureus Candida albicans hydrogel polyvinyl alcohol aliphatic dicarboxylic acids sustained release linezolid equilibrium swelling ratio accumulative release thermogravimetric analysis gram-negative bacteria multidrug resistance polymer therapeutics colistin polymyxin B nanoliposomes MDR-Bacteria chitosan nanotechnologies plant extracts agro-food-wastes antimicrobial agents polymeric nanocarriers mixed polymeric micelles drug delivery antibiotics Pluronic F127 antimicrobial agent polymeric nanomaterial self-assembly antimicrobial peptide silver nanoparticle anti-biofilm wound healing bromelain nisin bioactivity biomedicine carrier n/a
Functional Polymers as Innovative Tools in the Delivery of Antimicrobial Agents - Basel MDPI - Multidisciplinary Digital Publishing Institute 2022 - 1 electronic resource (222 p.)
Open Access
This Special Issue explored different topics concerning recent progress in the synthesis and characterization of suitable innovative macromolecular systems, proposed as carriers of specific antimicrobial molecules, to be employed in the biomedical and pharmaceutical fields. Many infectious diseases are induced by omnipresent micro-organisms, including bacteria, viruses, protozoa, fungi, and algae, and, consequently, are very common, accounting for a significant share of the global disease burden. Unfortunately, antimicrobial resistance, adverse effects, and the high cost of antimicrobials are crucial health challenges worldwide. One of the common efforts in addressing this issue lies in improving the existing antimicrobial delivery systems. In this regard, nanoparticles as well as three-dimensional hydrophilic systems represent valuable tools able to ensure excellent performances. Biocompatible polymeric particles, entrapping these bioactive molecules, are capable of releasing them over a desired period of time, thereby decreasing the frequency of their administration. At the same time, these systems are able to protect antimicrobial drugs from degradation, enhancing their bioavailability. This Special Issue serves to highlight and capture the contemporary progress recorded in this field.
Creative Commons
English
books978-3-0365-3622-4 9783036536217 9783036536224
10.3390/books978-3-0365-3622-4 doi
Research & information: general
film nanocomposite essential oil supercritical CO2 long-term package hybrid nanoparticles biocompatible polymer antimicrobial amphiphiles dynamic light scattering scanning electron microscopy cell viability from counting of colony-forming unities antimicrobial activity of nanoparticles Escherichia coli Staphylococcus aureus Candida albicans hydrogel polyvinyl alcohol aliphatic dicarboxylic acids sustained release linezolid equilibrium swelling ratio accumulative release thermogravimetric analysis gram-negative bacteria multidrug resistance polymer therapeutics colistin polymyxin B nanoliposomes MDR-Bacteria chitosan nanotechnologies plant extracts agro-food-wastes antimicrobial agents polymeric nanocarriers mixed polymeric micelles drug delivery antibiotics Pluronic F127 antimicrobial agent polymeric nanomaterial self-assembly antimicrobial peptide silver nanoparticle anti-biofilm wound healing bromelain nisin bioactivity biomedicine carrier n/a