Rare Respiratory Diseases: A Personal and a Public Health Problem
DasÃ, Francisco
Rare Respiratory Diseases: A Personal and a Public Health Problem - Basel MDPI - Multidisciplinary Digital Publishing Institute 2022 - 1 electronic resource (242 p.)
Open Access
Dear Colleagues, A rare disease, also known as an orphan disease, is any disease that affects a small percentage of the population. Although definitions vary from continent to continent, according to the European Union, rare diseases are those with a prevalence of less than 1 in 2000 people. Rare diseases are, in general, chronic, debilitating diseases, which in many cases threaten patients' lives. It is estimated that 1-2 million people in the European Union are affected by a rare respiratory disease, which is a public health problem. Due to the low prevalence and severity of many of these diseases, whose symptoms often initially manifest in childhood, combined efforts are needed to improve our knowledge of the pathophysiology of these diseases that will lead to the development of new, more effective treatments. Therefore, since rare respiratory diseases represent an important field in medicine, we propose this Special Issue to promote the dissemination of the latest advances in basic and clinical research in these diseases. Prof. Dr. Francisco Dasà Guest Editor
Creative Commons
English
books978-3-0365-3670-5 9783036536699 9783036536705
10.3390/books978-3-0365-3670-5 doi
Medicine
Pharmacology
standard diagnosis reference centres clinical presentation cilia primary ciliary dyskinesia alpha-1 antitrypsin deficiency rare respiratory diseases Mycobacterium avium Mycobacterium intracellulare nodular bronchiectasis non-tuberculous mycobacteria pulmonary aspergillosis rare pulmonary disease miRNA expression exhaled breath condensate sputum severity pulmonary exacerbation alpha1 antitrypsin deficiency augmentation therapy replacement therapy rare diseases gene therapy alpha-1-antitrypsin deficit cystic fibrosis neonatal respiratory distress laterality defect orphan diseases PCD immunofluorescence antibody ALI culture bio-resource primary nasal epithelium diagnostics Alpha-1 antitrypsin deficiency liver disease glutamate-oxaloacetate transaminase glutamate-pyruvate transaminase gamma-glutamyl transpeptidase resilience active lifestyle stress levels infection control measure self-quarantine flow cytometry nasal epithelium oxidative stress reactive oxygen species endoplasmic reticulum stress antioxidant therapies idiopathic pulmonary fibrosis chronic obstructive pulmonary disease bronchiectasis asthma emphysema alpha1-antitrypsin deficiency transient elastography n/a
Rare Respiratory Diseases: A Personal and a Public Health Problem - Basel MDPI - Multidisciplinary Digital Publishing Institute 2022 - 1 electronic resource (242 p.)
Open Access
Dear Colleagues, A rare disease, also known as an orphan disease, is any disease that affects a small percentage of the population. Although definitions vary from continent to continent, according to the European Union, rare diseases are those with a prevalence of less than 1 in 2000 people. Rare diseases are, in general, chronic, debilitating diseases, which in many cases threaten patients' lives. It is estimated that 1-2 million people in the European Union are affected by a rare respiratory disease, which is a public health problem. Due to the low prevalence and severity of many of these diseases, whose symptoms often initially manifest in childhood, combined efforts are needed to improve our knowledge of the pathophysiology of these diseases that will lead to the development of new, more effective treatments. Therefore, since rare respiratory diseases represent an important field in medicine, we propose this Special Issue to promote the dissemination of the latest advances in basic and clinical research in these diseases. Prof. Dr. Francisco Dasà Guest Editor
Creative Commons
English
books978-3-0365-3670-5 9783036536699 9783036536705
10.3390/books978-3-0365-3670-5 doi
Medicine
Pharmacology
standard diagnosis reference centres clinical presentation cilia primary ciliary dyskinesia alpha-1 antitrypsin deficiency rare respiratory diseases Mycobacterium avium Mycobacterium intracellulare nodular bronchiectasis non-tuberculous mycobacteria pulmonary aspergillosis rare pulmonary disease miRNA expression exhaled breath condensate sputum severity pulmonary exacerbation alpha1 antitrypsin deficiency augmentation therapy replacement therapy rare diseases gene therapy alpha-1-antitrypsin deficit cystic fibrosis neonatal respiratory distress laterality defect orphan diseases PCD immunofluorescence antibody ALI culture bio-resource primary nasal epithelium diagnostics Alpha-1 antitrypsin deficiency liver disease glutamate-oxaloacetate transaminase glutamate-pyruvate transaminase gamma-glutamyl transpeptidase resilience active lifestyle stress levels infection control measure self-quarantine flow cytometry nasal epithelium oxidative stress reactive oxygen species endoplasmic reticulum stress antioxidant therapies idiopathic pulmonary fibrosis chronic obstructive pulmonary disease bronchiectasis asthma emphysema alpha1-antitrypsin deficiency transient elastography n/a