Personalized Medicine in the Field of Inflammatory Skin Disorders
Tampa, Mircea
Personalized Medicine in the Field of Inflammatory Skin Disorders - Basel MDPI - Multidisciplinary Digital Publishing Institute 2022 - 1 electronic resource (262 p.)
Open Access
Skin inflammation is associated with a wide range of conditions which represent major health issues worldwide. Skin and mucosal surfaces represent the primary interface between the human body and the environment, susceptible to numerous factors whose action results in diseases produced by chemical substances, mechanical trauma, microbial agents, radiation, etc. Inflammation, a complex network of interactions between soluble molecules and cells, represents the main modality of the skin's response to injuries. Numerous studies have revealed close links between chronic inflammation, oxidative stress, and carcinogenesis. Chronic inflammation induces the activation of various cell types and an increase in the production of reactive oxygen species, promoting the initiation of a malignant process. Identifying specific biomarkers is essential for understanding molecular mechanisms and developing therapies appropriate to the patient's characteristics.Personalized medicine is an emerging field of medicine that has the potential to predict which therapy will be safe and efficacious for specific patients using an individual's genetic profile to guide decisions regarding the diagnosis, treatment, as well as prevention of disease. This book gathers articles that present recent advancements in research involving the mechanisms that underlie the development of inflammatory skin disorders, skin and mucosal inflammation in general.
Creative Commons
English
books978-3-0365-3573-9 9783036535746 9783036535739
10.3390/books978-3-0365-3573-9 doi
Medicine
sea-buckthorn seed oil long-chain fatty acids skin dysplastic keratinocytes UVA CD36 SR-B2 atopic dermatitis eczema JAK inhibitors systematic review meta-analysis evidence-based medicine immune-mediated skin diseases target therapy skin conditions and systemic inflammatory diseases systemic sclerosis biomarker calumenin S100A6 cytohesin 2 cannabinoids inflammation gut-lung-skin barrier signaling pathways inflammatory biomarkers psoriasis vulgaris prevalence comorbidities risk factors systemic lupus erythematous lupus nephritis lipid peroxidation DNA oxidation oxidized proteins carbohydrate oxidation antioxidative stress strategies biomarkers IgY psoriatic dermatitis imiquimod C57 BL/6 mice alginate biomaterial dressing fibers hydrogel nanofibers commercially available wound care wound healing cutaneous melanoma epigenetic regulation drug resistance therapeutic targets epigenetic therapy immune response Sutton nevi halo nevi skin tumor psoriasis proteome analysis estrogen menopause cSCC AK sialylation sialyltransferase sialidase COVID-19 pyoderma gangrenosum immunosuppression cyclosporine corticosteroids autoinflammatory disease androgenic alopecia clinical trial hair density platelet-rich plasma n/a
Personalized Medicine in the Field of Inflammatory Skin Disorders - Basel MDPI - Multidisciplinary Digital Publishing Institute 2022 - 1 electronic resource (262 p.)
Open Access
Skin inflammation is associated with a wide range of conditions which represent major health issues worldwide. Skin and mucosal surfaces represent the primary interface between the human body and the environment, susceptible to numerous factors whose action results in diseases produced by chemical substances, mechanical trauma, microbial agents, radiation, etc. Inflammation, a complex network of interactions between soluble molecules and cells, represents the main modality of the skin's response to injuries. Numerous studies have revealed close links between chronic inflammation, oxidative stress, and carcinogenesis. Chronic inflammation induces the activation of various cell types and an increase in the production of reactive oxygen species, promoting the initiation of a malignant process. Identifying specific biomarkers is essential for understanding molecular mechanisms and developing therapies appropriate to the patient's characteristics.Personalized medicine is an emerging field of medicine that has the potential to predict which therapy will be safe and efficacious for specific patients using an individual's genetic profile to guide decisions regarding the diagnosis, treatment, as well as prevention of disease. This book gathers articles that present recent advancements in research involving the mechanisms that underlie the development of inflammatory skin disorders, skin and mucosal inflammation in general.
Creative Commons
English
books978-3-0365-3573-9 9783036535746 9783036535739
10.3390/books978-3-0365-3573-9 doi
Medicine
sea-buckthorn seed oil long-chain fatty acids skin dysplastic keratinocytes UVA CD36 SR-B2 atopic dermatitis eczema JAK inhibitors systematic review meta-analysis evidence-based medicine immune-mediated skin diseases target therapy skin conditions and systemic inflammatory diseases systemic sclerosis biomarker calumenin S100A6 cytohesin 2 cannabinoids inflammation gut-lung-skin barrier signaling pathways inflammatory biomarkers psoriasis vulgaris prevalence comorbidities risk factors systemic lupus erythematous lupus nephritis lipid peroxidation DNA oxidation oxidized proteins carbohydrate oxidation antioxidative stress strategies biomarkers IgY psoriatic dermatitis imiquimod C57 BL/6 mice alginate biomaterial dressing fibers hydrogel nanofibers commercially available wound care wound healing cutaneous melanoma epigenetic regulation drug resistance therapeutic targets epigenetic therapy immune response Sutton nevi halo nevi skin tumor psoriasis proteome analysis estrogen menopause cSCC AK sialylation sialyltransferase sialidase COVID-19 pyoderma gangrenosum immunosuppression cyclosporine corticosteroids autoinflammatory disease androgenic alopecia clinical trial hair density platelet-rich plasma n/a