Comorbidities in Chronic Kidney Disease (CKD)
Jankowski, Joachim
Comorbidities in Chronic Kidney Disease (CKD) - Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021 - 1 electronic resource (184 p.)
Open Access
With a mean worldwide prevalence of 13%, chronic kidney disease imposes a massive health burden on our society. In addition to reduced kidney function, patients with chronic kidney disease increasingly suffer from cardiovascular diseases affecting the heart and vasculature. Cardiovascular diseases account for around half of the deaths of patients with advanced chronic kidney disease. However, therapeutic options are highly insufficient. The pathological mechanisms that underlie increased cardiovascular risk in patients with chronic kidney disease remain largely unknown. This Special Issue provides insights into comorbidities in CKD patients, mainly focused on increased cardiovascular risk, and summarizes current knowledge of underlying pathophysiological mechanisms.
Creative Commons
English
books978-3-03936-669-9 9783039366682 9783039366699
10.3390/books978-3-03936-669-9 doi
Medicine
arterial stiffness carotid-femoral pulse wave velocity hemodialysis p-cresyl sulfate uremic toxins arterial calcification lipid metabolism inflammation coagulation endothelial dysfunction epigenetics chronic kidney disease uremic cardiopathy left ventricular hypertrophy phosphate PTH FGF23 klotho sclerostin chronodisruption chronodisruptor circadian rhythm internal clock uremia uremic cardiomyopathy organ crosstalk cardiorenal syndrome left-ventricular hypertrophy heart failure cardiac fibrosis cardiovascular disease vascular calcification experimental rodent models FGFG23 Klotho Wnt/β-catenin CKD parathyroid hormone secondary hyperparathyroidism uremic toxin ageing end-stage kidney disease premature ageing senescence bone gut cardiovascular CKD-MBD comorbidity fibrosis calcification
Comorbidities in Chronic Kidney Disease (CKD) - Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021 - 1 electronic resource (184 p.)
Open Access
With a mean worldwide prevalence of 13%, chronic kidney disease imposes a massive health burden on our society. In addition to reduced kidney function, patients with chronic kidney disease increasingly suffer from cardiovascular diseases affecting the heart and vasculature. Cardiovascular diseases account for around half of the deaths of patients with advanced chronic kidney disease. However, therapeutic options are highly insufficient. The pathological mechanisms that underlie increased cardiovascular risk in patients with chronic kidney disease remain largely unknown. This Special Issue provides insights into comorbidities in CKD patients, mainly focused on increased cardiovascular risk, and summarizes current knowledge of underlying pathophysiological mechanisms.
Creative Commons
English
books978-3-03936-669-9 9783039366682 9783039366699
10.3390/books978-3-03936-669-9 doi
Medicine
arterial stiffness carotid-femoral pulse wave velocity hemodialysis p-cresyl sulfate uremic toxins arterial calcification lipid metabolism inflammation coagulation endothelial dysfunction epigenetics chronic kidney disease uremic cardiopathy left ventricular hypertrophy phosphate PTH FGF23 klotho sclerostin chronodisruption chronodisruptor circadian rhythm internal clock uremia uremic cardiomyopathy organ crosstalk cardiorenal syndrome left-ventricular hypertrophy heart failure cardiac fibrosis cardiovascular disease vascular calcification experimental rodent models FGFG23 Klotho Wnt/β-catenin CKD parathyroid hormone secondary hyperparathyroidism uremic toxin ageing end-stage kidney disease premature ageing senescence bone gut cardiovascular CKD-MBD comorbidity fibrosis calcification