Liver regeneration and carcinogenesis : molecular and cellular mechanisms /
Liver regeneration and carcinogenesis : molecular and cellular mechanisms /
edited by Randy L. Jirtle.
- San Diego : Academic Press, ©1995.
- 1 online resource (xxiii, 402 pages) : illustrations
Includes bibliographical references and index.
Liver Regeneration, Then and Now. Hepatocyte Growth Factor (HGF) and Its Receptor (MET) in Liver Regeneration, Neoplasia, And Disease. Structure and Functions of the HGF Receptor (C-Met). Expression and Function of Growth-Induced Genes During Liver Regeneration. Stem Cells and Hepatocarcinogenesis. Contributions of Hepadnavirus Research to Our Understanding of Hepatocarcinogenesis. Apoptosis and Hepatocarcinogenesis. Liver Tumor Promotion and the Suppression of P53-Dependant Cell Cycle Checkpoint Function. Mechanisms of Liver Tumor Promotion. Hypomethylation of DNA: A Epigenetic Mechanism that Can Facilitate the Aberrant Oncogene Expression Involved in Liver Carcinogenesis. Transgene-Based Strategies for Studying Liver Growth, Development and Cancer. Subject Index.
Use copy
Because of its marked capacity to regenerate and the ability of chemical carcinogens and viruses to ready transform hepatocytes, the liver has been used extensively as a model for investigating the molecular mechanisms of cellular proliferation and carcinogenesis. Recently, striking advances have occured in the understanding of hepatocyte growth regulation and the manner in which chemical agents and viruses alter these normal growth regulatory pathways in liver carcinogenesis. This explosion of information has occured in a multitude of researh disciplines. This book brings together current findings in a coherent manner, from a molecular point of view. Three sections cover in detail the areas of liver regeneration, liver carcinogenesis, and liver tumor therapy. The contributors are pioneers and leaders in this field. * Logical organization of material in three detailed and comprehensive sections: liver regeneration, liver carcinogenesis, and liver tumor treatment * Contributors are pioneers and leaders in the field * There are currently no books on this subject on the market * Research focus is at the molecular level.
Electronic reproduction.
[Place of publication not identified] :
HathiTrust Digital Library,
2010.
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.
http://purl.oclc.org/DLF/benchrepro0212
9780123853554 0123853559 9780080535548 (electronic bk.) 0080535542 (electronic bk.)
88515:88515 Elsevier Science & Technology http://www.sciencedirect.com
Liver--Cancer.
Liver--Regeneration.
Pathology, Molecular.
Liver--Molecular aspects.
Liver Regeneration.
Liver Neoplasms--genetics.
MEDICAL--Hepatology.
Liver--Cancer.
Liver--Regeneration.
Pathology, Molecular.
Humans Liver Diseases
Electronic books.
RC280.L5 / L587 1995eb
616.3/62
1995 K-369 WI 702 / L7848 1995
Includes bibliographical references and index.
Liver Regeneration, Then and Now. Hepatocyte Growth Factor (HGF) and Its Receptor (MET) in Liver Regeneration, Neoplasia, And Disease. Structure and Functions of the HGF Receptor (C-Met). Expression and Function of Growth-Induced Genes During Liver Regeneration. Stem Cells and Hepatocarcinogenesis. Contributions of Hepadnavirus Research to Our Understanding of Hepatocarcinogenesis. Apoptosis and Hepatocarcinogenesis. Liver Tumor Promotion and the Suppression of P53-Dependant Cell Cycle Checkpoint Function. Mechanisms of Liver Tumor Promotion. Hypomethylation of DNA: A Epigenetic Mechanism that Can Facilitate the Aberrant Oncogene Expression Involved in Liver Carcinogenesis. Transgene-Based Strategies for Studying Liver Growth, Development and Cancer. Subject Index.
Use copy
Because of its marked capacity to regenerate and the ability of chemical carcinogens and viruses to ready transform hepatocytes, the liver has been used extensively as a model for investigating the molecular mechanisms of cellular proliferation and carcinogenesis. Recently, striking advances have occured in the understanding of hepatocyte growth regulation and the manner in which chemical agents and viruses alter these normal growth regulatory pathways in liver carcinogenesis. This explosion of information has occured in a multitude of researh disciplines. This book brings together current findings in a coherent manner, from a molecular point of view. Three sections cover in detail the areas of liver regeneration, liver carcinogenesis, and liver tumor therapy. The contributors are pioneers and leaders in this field. * Logical organization of material in three detailed and comprehensive sections: liver regeneration, liver carcinogenesis, and liver tumor treatment * Contributors are pioneers and leaders in the field * There are currently no books on this subject on the market * Research focus is at the molecular level.
Electronic reproduction.
[Place of publication not identified] :
HathiTrust Digital Library,
2010.
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.
http://purl.oclc.org/DLF/benchrepro0212
9780123853554 0123853559 9780080535548 (electronic bk.) 0080535542 (electronic bk.)
88515:88515 Elsevier Science & Technology http://www.sciencedirect.com
Liver--Cancer.
Liver--Regeneration.
Pathology, Molecular.
Liver--Molecular aspects.
Liver Regeneration.
Liver Neoplasms--genetics.
MEDICAL--Hepatology.
Liver--Cancer.
Liver--Regeneration.
Pathology, Molecular.
Humans Liver Diseases
Electronic books.
RC280.L5 / L587 1995eb
616.3/62
1995 K-369 WI 702 / L7848 1995