Rethinking homeostasis : allostatic regulation in physiology and pathophysiology /
Schulkin, Jay.
Rethinking homeostasis : allostatic regulation in physiology and pathophysiology / Jay Schulkin. - Cambridge, Mass. : MIT Press, ©2003. - 1 online resource (xvi, 296 pages) : illustrations. - Bradford Bks. . - Bradford Bks. .
"A Bradford book."
Includes bibliographical references (pages 175-277) and indexes.
Preface -- Introduction -- Allostasis : the emergence of a concept -- Central motive states : feedforward neuroendocrine systems in the brain -- Anticipation, angst, allostatic regulation : adrenal steroid regulation of corticotropin-releasing hormone -- Normal and pathological facilitation of parturition by a feedforward endocrine mechanism -- Addiction to drugs : allostatic regulation under duress -- Conclusion. 1. 2. 3. 4. 5.
Homeostasis, a key concept in biology, refers to the tendency toward stability in the various bodily states that make up the internal environment. Examples include temperature regulation and oxygen consumption. The body's needs, however, do not remain constant. When an organism is under stress, the central nervous system works with the endocrine system to use resources to maintain the overall viability of the organism. The process accelerates the various systems' defenses of bodily viability, but can violate short-term homeostasis. This allostatic regulation highlights our ability to anticipate, adapt to, and cope with impending future events. In Rethinking Homeostasis, Jay Schulkin defines and explores many aspects of allostasis, including the wear and tear on tissues and accelerated pathophysiology caused by allostatic overload. Focusing on the concept of motivation and its relationship to the central nervous system function and specific hormonal systems, he applies a neuroendocrine perspective to central motive states such as cravings for water, sodium, food, sex, and drugs. He examines in detail the bodily consequences of the behavioral and neuroendocrine regulation of fear and adversity, the endocrine regulation of normal and preterm birth, and the effects of drug addiction on the body. Schulkin's presentation of allostasis lays the foundation for further study.
English.
9780262283274 (electronic bk.) 0262283271 (electronic bk.) 0585446601 (electronic bk.) 9780585446608 (electronic bk.) 9780262194808 0262194805 (Trade Cloth) 0262293587 9780262293587
00015994 5928 MIT Press 9780262283274 MIT Press
Homeostasis.
Neuroendocrinology.
Psychophysiology.
Biological control systems.
Homeostasis
Neurosecretory Systems--physiology
Psychophysiology
Neuroendocrinology
Homéostasie.
Neuroendocrinologie.
Psychophysiologie.
Régulation (Biologie)
MEDICAL--Physiology.
SCIENCE--Life Sciences--Human Anatomy & Physiology.
Biological control systems.
Homeostasis.
Neuroendocrinology.
Psychophysiology.
Homeostase.
Fysiologie.
Regelmechanismen.
NEUROSCIENCE/General
Electronic books.
Electronic books.
QP90.4 / .S38 2003eb
612/.022
QT 120 / S386r 2003
Rethinking homeostasis : allostatic regulation in physiology and pathophysiology / Jay Schulkin. - Cambridge, Mass. : MIT Press, ©2003. - 1 online resource (xvi, 296 pages) : illustrations. - Bradford Bks. . - Bradford Bks. .
"A Bradford book."
Includes bibliographical references (pages 175-277) and indexes.
Preface -- Introduction -- Allostasis : the emergence of a concept -- Central motive states : feedforward neuroendocrine systems in the brain -- Anticipation, angst, allostatic regulation : adrenal steroid regulation of corticotropin-releasing hormone -- Normal and pathological facilitation of parturition by a feedforward endocrine mechanism -- Addiction to drugs : allostatic regulation under duress -- Conclusion. 1. 2. 3. 4. 5.
Homeostasis, a key concept in biology, refers to the tendency toward stability in the various bodily states that make up the internal environment. Examples include temperature regulation and oxygen consumption. The body's needs, however, do not remain constant. When an organism is under stress, the central nervous system works with the endocrine system to use resources to maintain the overall viability of the organism. The process accelerates the various systems' defenses of bodily viability, but can violate short-term homeostasis. This allostatic regulation highlights our ability to anticipate, adapt to, and cope with impending future events. In Rethinking Homeostasis, Jay Schulkin defines and explores many aspects of allostasis, including the wear and tear on tissues and accelerated pathophysiology caused by allostatic overload. Focusing on the concept of motivation and its relationship to the central nervous system function and specific hormonal systems, he applies a neuroendocrine perspective to central motive states such as cravings for water, sodium, food, sex, and drugs. He examines in detail the bodily consequences of the behavioral and neuroendocrine regulation of fear and adversity, the endocrine regulation of normal and preterm birth, and the effects of drug addiction on the body. Schulkin's presentation of allostasis lays the foundation for further study.
English.
9780262283274 (electronic bk.) 0262283271 (electronic bk.) 0585446601 (electronic bk.) 9780585446608 (electronic bk.) 9780262194808 0262194805 (Trade Cloth) 0262293587 9780262293587
00015994 5928 MIT Press 9780262283274 MIT Press
Homeostasis.
Neuroendocrinology.
Psychophysiology.
Biological control systems.
Homeostasis
Neurosecretory Systems--physiology
Psychophysiology
Neuroendocrinology
Homéostasie.
Neuroendocrinologie.
Psychophysiologie.
Régulation (Biologie)
MEDICAL--Physiology.
SCIENCE--Life Sciences--Human Anatomy & Physiology.
Biological control systems.
Homeostasis.
Neuroendocrinology.
Psychophysiology.
Homeostase.
Fysiologie.
Regelmechanismen.
NEUROSCIENCE/General
Electronic books.
Electronic books.
QP90.4 / .S38 2003eb
612/.022
QT 120 / S386r 2003