The "Calcium Paradox" and its Impact on Neurological and Psychiatric Diseases /

Bergantin, Leandro Bueno,

The "Calcium Paradox" and its Impact on Neurological and Psychiatric Diseases / Leandro Bueno Bergantin and Afonso Caricati-Neto. - Second edition. - 1 online resource

Includes bibliographical references.

8.2 Amyloid -Peptide endorses Ca2+ Influx and a Ca2+- Mediated Excitotoxicity8.2.1 Presenilins; 8.3 Cytoskeletal pathology in AD and Ca2+; 8.4 Ca2+ Actions Upstream of the Amyloidogenesis; 8.5 Synapses and Ca2+; 8.6 Selectivity of the Neuronal Vulnerability in AD and Ca2+; 8.7 Improving Neuronal Ca2+ Homeostasis as a Therapeutic Approach for AD; 8.8 Reasonable mechanisms for healthy brain aging and AD; Chapter Nine; Chapter Ten; Chapter Eleven; Bibliography; About the Authors.

This book extends the original concept of the ""calcium paradox"" discovery, herein compiling more than 300 references in the field of calcium ion (Ca2+/cAMP) signalling pathways, neurotransmission and neurodegeneration, and neurological and psychiatric diseases. In this second edition, novel illustrations and tables (highlighting current medicines for treating these diseases, including their mechanism of action) offer improved insights into the concepts for students and clinicians. The description of other neurodegenerative diseases (Spinal muscular atrophy, Amyotrophic Lateral Sclerosis and.

9781527518346 (electronic bk.) 1527518345 (electronic bk.)


Nervous system--Diseases--Pathophysiology.
Calcium channels.
Calcium Channels--physiology
Nervous System Diseases--metabolism
Mental Disorders--metabolism
Calcium Channels
Système nerveux--Maladies.
Canaux à calcium.
HEALTH & FITNESS--Diseases--General.
MEDICAL--Clinical Medicine.
MEDICAL--Diseases.
MEDICAL--Evidence-Based Medicine.
MEDICAL--Internal Medicine.
Calcium channels.


Electronic books.
Electronic books.

RC346

616.8/047

2018 H-341 QU 55.7

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