The advanced handbook of methods in evidence based healthcare / edited by Andrew Stevens [and others].

Includes bibliographical references and index.

Print version record.

This text provides a comprehensive, state-of-the-art review of the available methods of health care evaluation.

Contributors -- Introduction: Methods in Evidence Based Healthcare and Health Technology Assessment: An Overview -- pt. I. Clinical Trials -- Introduction -- 1. Ethical Issues in the Design and Conduct of Randomised Controlled Trials -- 2. Ethics of Clinical Trials: Social, Cultural and Economic Factors -- 3. Factors that Limits the Number, Progress and Quality of Randomised Controlled Trials: A Systematic Review -- 4. Results of Clinical Trials and Systematic Reviews: To Whom Do They Apply? -- 5. The Placebo Effect: Methodological Process and Implications of a Structured Review -- pt. II. Observational and Qualitative Methods -- Introduction -- 6. Randomised and Non-Randomised Studies: Threats to Internal and External Validity -- 7. A Review of Observational, Quasi-Experimental and Randomised Study Designs for the Evaluation of the Effectiveness of Healthcare Interventions -- 8. The Potential Use of Routine Datasets in Health Technology Assessment -- 9. Using Routine Data to Complement and Enhance the Results of Randomised Controlled Trials -- 10. Qualitative Methods in Health Technology Assessment -- pt. III. Measurement of Benefit and Cost -- Introduction -- 11. Criteria for Assessing Patient Based Outcome Measures for Use in Clinical Trials -- 12. The Use of Health Status Measures in Economic Evaluation -- 13. Collecting Resource Use Data for Costing in Clinical Trials -- 14. Eliciting Time Preferences for Health -- 15. The Conduct and Design of Questionnaire Surveys in Healthcare Research -- pt. IV. Analytical Methods -- Introduction -- 16. Bayesian Methods -- 17. Methods for Evaluating Organisation- or Area-Based Health Interventions -- 18. Handling Uncertainty in Economic Evaluation -- 19. A Review of the Use of the Main Quality of Life Measures, and Sample Size Determination for Quality of Life Measures, Particularly in Cancer Clinical Trials -- 20. Simultaneous Analysis of Quality of Life and Survival Data -- pt. V. Consensus, Reviews and Meta-Analysis -- Introduction -- 21. Publication and Related Biases -- 22. Meta-Analysis in Health Technology Assessment -- 23. Assessing the Quality of Reports of Randomised Trials Included in Meta-Analyses: Attitudes, Practice, Evidence and Guides -- 24. Consensus Development Methods, and their Use in Creating Clinical Guidelines -- pt. VI. Identifying and Filling Gaps in the Evidence -- Introduction -- 25. Identifying New Healthcare Technologies -- 26. Timing of Assessment of Fast-Changing Health Technologies -- 27. Preliminary Economic Evaluation of Health Technologies -- Index.

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